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galactokinase 1

Summary

Gene Symbol

GALK1

Organism

Gorilla gorilla gorilla (western lowland gorilla)

External Links

NCBI Gene: 101138686
KEGG Gene ID: ggo:101138686
PubChem: 101138686

Annotation

Keyword

ATP-binding
Galactose metabolism
Kinase
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
G3R272	Galactose kinase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
carbohydrate phosphorylation	IEA	22301074
galactose metabolic process	IEA	22301074 30032202

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

carbohydrate phosphorylation

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

galactose metabolic process

carbohydrate phosphorylation

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

galactose metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

galactose metabolic process

carbohydrate phosphorylation

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

carbohydrate phosphorylation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cytosol	IEA	30032202
cytoplasm	IEA	22301074

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
galactokinase activity	IEA	22301074 30032202
ATP binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

carbohydrate kinase activity [inference]

galactokinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

galactokinase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Hominidae

Group Name

GHMP kinase, C-terminal domain

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
I: Lipid transport and metabolism

Displaying entries **1 - 10** of 14 in total

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Gene Ontology
ATP binding
L-arabinokinase activity
carbohydrate phosphorylation
galactitol metabolic process
galactokinase activity
galactose binding
galactose catabolic process via UDP-galactose
galactose metabolic process
glycolytic process from galactose
kinase activity

Displaying **all 10** entries
InterPro
GHMP kinase N-terminal domain
GHMP kinase, ATP-binding, conserved site
GHMP kinase, C-terminal domain superfamily
GHMP kinase, C-terminal domain
Galactokinase, N-terminal domain
Galactokinase, conserved site
Galactokinase
Mevalonate/galactokinase
Ribosomal protein uS5 domain 2-type superfamily
Small ribosomal subunit protein uS5 domain 2-type fold, subgroup

KEGG BRITE Database

Orthology

K00849

Name

galactokinase [EC:2.7.1.6]

References

3158881

Rhea

α-D-galactose + ATP

H⁺ + ADP + α-D-galactose 1-phosphate

Enzyme

2.7.1.6

PMID

Ortholog

Displaying entries **1 - 10** of 70 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	2584	9606_0:00367a		HUMAN36317
Mus musculus	14635			MOUSE03510
Rattus norvegicus	287835			RATNO01682
Canis lupus familiaris	403694			CANLF18446
Danio rerio	449829			DANRE03363
Pan troglodytes	454888	9598_0:004649		PANTR15450
Bos taurus	530855			BOVIN13974
Macaca mulatta	703873			MACMU14236
Monodelphis domestica	100027229			MONDO11332
Ciona intestinalis	100177329			CIOIN06768

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024