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Standards Ontologies Notations
steroid 5 alpha-reductase 2

Summary
Gene Symbol
  • SRD5A2
Organism
Gorilla gorilla gorilla (western lowland gorilla)
NCBI Gene
101138758
KEGG Gene ID
ggo:101138758
PubChem
101138758
Annotation
Keyword
  • Microsome
  • Reference proteome
  • Sexual differentiation
  • Transmembrane helix
Proteins
Displaying 1 entry
UniProt Protein Name
G3RPI7
Annotation information from UniProt.
Gene Ontology (GO)
Displaying 1 entry
GO Term Evidence Code PMID
membrane
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Hominidae
Group Name
3-oxo-5-alpha-steroid 4-dehydrogenase
Functional Category
  • I: Lipid transport and metabolism
  • O: Posttranslational modification, protein turnover, chaperones
Displaying entries 1 - 10 of 16 in total
Gene Ontology
3-oxo-5-alpha-steroid 4-dehydrogenase activity
3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) activity
androgen biosynthetic process
androgen metabolic process
brassinosteroid biosynthetic process
lipid metabolic process
male genitalia development
male gonad development
oxidoreductase activity, acting on the CH-CH group of donors
oxidoreductase activity
Displaying all 3 entries
InterPro
3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal
3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase
3-oxo-5-alpha-steroid 4-dehydrogenase
KEGG BRITE Database
Orthology
K12344
Name
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
References
Rhea

RHEA:54384

a 3-oxo-5α-steroid + NADP+
H+ + a 3-oxo-Δ4-steroid + NADPH
Enzyme
PMID

RHEA:21952

5α-pregnane-3,20-dione + NADP+
H+ + progesterone + NADPH
Enzyme
PMID

RHEA:50820

17β-hydroxy-5α-androstan-3-one + NADP+
H+ + testosterone + NADPH
Enzyme
PMID
Ortholog
Displaying entries 51 - 57 of 57 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
115596855 SPAAU09713
115613952 STRHB13681
116441079 CORMO18853
117033123 RHIFE24936
122215122 PANLE02263
123799861 URSAM06602
129030531 9600_0:000a7b
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024