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phosphatidylinositol 3-kinase catalytic subunit type 3

Summary

Gene Symbol

PIK3C3

Organism

Orcinus orca (killer whale)

External Links

NCBI Gene: 101273072
KEGG Gene ID: oor:101273072
PubChem: 101273072

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
endocytosis	IEA	30032202
autophagy of peroxisome	IEA	30032202
phosphatidylinositol-mediated signaling	IEA	30032202
autophagosome assembly	IEA	30032202
phosphatidylinositol-3-phosphate biosynthetic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

autophagy of peroxisome

biosynthetic process [inference]

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phosphatidylinositol metabolic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phosphatidylinositol metabolic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

cellular catabolic process [inference]

autophagy [inference]

autophagy of peroxisome

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phosphatidylinositol metabolic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phosphatidylinositol metabolic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phosphatidylinositol metabolic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phosphatidylinositol metabolic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phosphatidylinositol metabolic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phosphatidylinositol metabolic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phosphatidylinositol metabolic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

phosphatidylinositol-mediated signaling

vesicle-mediated transport [inference]

endocytosis

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phosphatidylinositol metabolic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phosphatidylinositol metabolic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

cellular catabolic process [inference]

autophagy [inference]

autophagy of peroxisome

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phosphatidylinositol metabolic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

phosphatidylinositol metabolic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process [inference]

phosphatidylinositol-3-phosphate biosynthetic process

process utilizing autophagic mechanism [inference]

autophagy [inference]

autophagy of peroxisome

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vacuole organization [inference]

autophagosome organization [inference]

autophagosome assembly

organelle assembly [inference]

autophagosome assembly

cellular component assembly [inference]

organelle assembly [inference]

autophagosome assembly

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis

import into cell [inference]

endocytosis

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

phosphatidylinositol-mediated signaling

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
membrane	IEA	30032202
phagophore assembly site	IEA	30032202
peroxisome	IEA	30032202
phosphatidylinositol 3-kinase complex, class III, type II	IEA	30032202
phosphatidylinositol 3-kinase complex, class III, type I	IEA	30032202

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

phosphatidylinositol 3-kinase complex [inference]

phosphatidylinositol 3-kinase complex, class III [inference]

catalytic complex [inference]

transferase complex [inference]

transferase complex, transferring phosphorus-containing groups [inference]

phosphatidylinositol 3-kinase complex [inference]

phosphatidylinositol 3-kinase complex, class III [inference]

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

Displaying 1 entry
GO Term	Evidence Code	PMID
1-phosphatidylinositol-3-kinase activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

lipid kinase activity [inference]

phosphatidylinositol kinase activity [inference]

1-phosphatidylinositol-3-kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

phosphatidylinositol kinase activity [inference]

1-phosphatidylinositol-3-kinase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Cetacea

Group Name

phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 8** entries
Gene Ontology
ATP binding
autophagosome assembly
kinase activity
nucleotide binding
phosphatidylinositol-3-phosphate biosynthetic process
phosphatidylinositol-mediated signaling
phosphorylation
transferase activity

Displaying entries **1 - 10** of 11 in total

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InterPro
Armadillo-type fold
C2 domain superfamily
C2 phosphatidylinositol 3-kinase-type domain
Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily
Phosphatidylinositol 3-/4-kinase, catalytic domain
Phosphatidylinositol 3-kinase, Vps34 type
Phosphatidylinositol 3/4-kinase, conserved site
Phosphatidylinositol kinase
Phosphoinositide 3-kinase, accessory (PIK) domain superfamily
Phosphoinositide 3-kinase, accessory (PIK) domain

KEGG BRITE Database

Orthology

K00914

Name

phosphatidylinositol 3-kinase [EC:2.7.1.137]

References

7628435

Ortholog

Displaying entries **1 - 10** of 12 in total

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Species	Gene ID	OrthoDB
Tursiops truncatus	101327315	9739_0:00313e
Physeter catodon	102975170	9755_0:003a46
Balaenoptera acutorostrata	103003736	9767_0:003506
Lipotes vexillifer	103069584	118797_0:00319b
Delphinapterus leucas	111168878	9749_0:004293
Neophocaena asiaeorientalis asiaeorientalis	112410059	1706337_0:002e14
Lagenorhynchus obliquidens	113631372	90247_0:002680
Monodon monoceros	114894479	40151_0:0002a3
Globicephala melas	115845781	9731_0:003f7c
Phocoena sinus	116738765	42100_0:003530

GlyTouCan

GlyComb

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UniCarb-DR

LM-GlycoRepo

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Summary

External Links

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements