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phospholipase C zeta 1

Summary

Gene Symbol

PLCZ1

Organism

Odobenus rosmarus divergens (Pacific walrus)

External Links

NCBI Gene: 101377048
KEGG Gene ID: oro:101377048
PubChem: 101377048

Annotation

Keyword

Developmental protein
Fertilization
Hydrolase
Lipid degradation
Reference proteome
Transducer

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A2U3WJW5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
positive regulation of cytosolic calcium ion concentration involved in egg activation	IEA	30032202
intracellular signal transduction	IEA	22301074 30032202
lipid metabolic process	IEA	22301074

GO Hierarchy

biological process

metabolic process [inference]

primary metabolic process [inference]

lipid metabolic process

organic substance metabolic process [inference]

lipid metabolic process

cellular process [inference]

signal transduction [inference]

intracellular signal transduction

reproductive process [inference]

positive regulation of cytosolic calcium ion concentration involved in egg activation

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration [inference]

positive regulation of cytosolic calcium ion concentration involved in egg activation

Displaying 1 entry
GO Term	Evidence Code	PMID
nucleus	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying 1 entry
GO Term	Evidence Code	PMID
phosphatidylinositol phospholipase C activity	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

lipase activity [inference]

phospholipase activity [inference]

phospholipase C activity [inference]

phosphatidylinositol phospholipase C activity

phosphoric ester hydrolase activity [inference]

phosphoric diester hydrolase activity [inference]

phospholipase C activity [inference]

phosphatidylinositol phospholipase C activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Carnivora

Group Name

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1

Functional Category

O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
hydrolase activity
lipid metabolic process
phosphatidylinositol phospholipase C activity
phosphatidylinositol-mediated signaling
positive regulation of cytosolic calcium ion concentration involved in egg activation
release of sequestered calcium ion into cytosol
single fertilization

Displaying **all 6** entries
InterPro
C2 domain superfamily
C2 domain
PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
Phosphatidylinositol-specific phospholipase C, X domain
Phosphoinositide phospholipase C family
Phospholipase C, phosphatidylinositol-specific, Y domain

KEGG BRITE Database

Orthology

K05861

Name

phosphatidylinositol phospholipase C, zeta [EC:3.1.4.11]

References

Rhea

RHEA:33179

H₂O + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate)

H⁺ + a 1,2-diacyl-sn-glycerol + 1D-myo-inositol 1,4,5-trisphosphate

Enzyme

3.1.4.11

PMID

Ortholog

Displaying entries **11 - 20** of 43 in total

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Callorhinus ursinus	112830134	34884_0:001e0b
Puma concolor	112867620	9696_0:003b05
Vulpes vulpes	112917544	9627_0:0010f4
Ursus arctos	113257833	9644_0:00314e
Zalophus californianus	113922509	9704_0:002bc1
Eumetopias jubatus	114221599	34886_0:002d9e
Suricata suricatta	115304450	37032_0:002ca3
Lynx canadensis	115519341	61383_0:001e18

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements