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4-hydroxy-2-oxoglutarate aldolase 1

Summary

Gene Symbol

HOGA1

Organism

Odobenus rosmarus divergens (Pacific walrus)

External Links

NCBI Gene: 101385318
KEGG Gene ID: oro:101385318
PubChem: 101385318

Annotation

Keyword

Lyase
Reference proteome
Schiff base

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A2U3WKY9
A0A2U3WKU3	Dihydrodipicolinate synthase-like Probable 2-keto-4-hydroxyglutarate aldolase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
N-acetylneuraminate catabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound catabolic process [inference]

N-acetylneuraminate catabolic process

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

carbohydrate derivative catabolic process [inference]

amino sugar catabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound catabolic process [inference]

N-acetylneuraminate catabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

carbohydrate derivative metabolic process [inference]

amino sugar metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

amino sugar catabolic process [inference]

N-acetylneuraminate catabolic process

carbohydrate derivative catabolic process [inference]

amino sugar catabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound catabolic process [inference]

N-acetylneuraminate catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

carbohydrate derivative catabolic process [inference]

amino sugar catabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound catabolic process [inference]

N-acetylneuraminate catabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
4-hydroxy-tetrahydrodipicolinate synthase activity	IEA	30032202
N-acetylneuraminate lyase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

lyase activity [inference]

carbon-carbon lyase activity [inference]

oxo-acid-lyase activity [inference]

N-acetylneuraminate lyase activity

carbon-oxygen lyase activity [inference]

hydro-lyase activity [inference]

4-hydroxy-tetrahydrodipicolinate synthase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Carnivora

Group Name

4-hydroxy-2-oxoglutarate aldolase, mitochondrial

Functional Category

I: Lipid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 6** entries
Gene Ontology
4-hydroxy-2-oxoglutarate aldolase activity
4-hydroxy-tetrahydrodipicolinate synthase activity
glyoxylate catabolic process
lyase activity
oxo-acid-lyase activity
small molecule metabolic process

Displaying **all 3** entries
InterPro
Aldolase-type TIM barrel
DapA-like
Schiff base-forming aldolase, active site

KEGG BRITE Database

Orthology

K18123

Name

4-hydroxy-2-oxoglutarate aldolase [EC:4.1.3.16]

References

21998747

Rhea

(4R)-4-hydroxy-2-oxoglutarate

pyruvate + glyoxylate

Enzyme

4.1.3.16

PMID

5780845

(4S)-4-hydroxy-2-oxoglutarate

pyruvate + glyoxylate

Enzyme

PMID

Ortholog

Displaying entries **1 - 10** of 44 in total

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Next ›

Last »
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Canis lupus familiaris	608755	9615_1:0043e5
Ailuropoda melanoleuca	100478059	9646_0:001b8d
Felis catus	101101417	9685_0:003608
Mustela putorius furo	101693912	9669_0:0041b7
Leptonychotes weddellii	102740193	9713_0:002410
Panthera tigris	102965487	9694_0:003607
Ursus maritimus	103674087	29073_0:004bf2
Acinonyx jubatus	106966929	32536_0:002aba
Panthera pardus	109272717	9691_0:002e48
Neomonachus schauinslandi	110589086	29088_0:001f7f

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GlyCosmos Portal v4.1.0

Last updated: December 9, 2024