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lysophosphatidic acid receptor 6

Summary

Gene Symbol

LPAR6

Organism

Homo sapiens (human)

External Links

NCBI Gene

10161

PubChem

10161

Alliance of Genome Resources

HGNC:15520

Annotation

Keyword

Cell membrane
Disease variant
Disulfide bond
G-protein coupled receptor
Glycoprotein
Hypotrichosis
Palmitate
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B3KVQ5
P43657	Oleoyl-L-alpha-lysophosphatidic acid receptor P2Y purinoceptor 5 Purinergic receptor 5 RB intron encoded G-protein coupled receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
G protein-coupled receptor signaling pathway	IBA
phospholipase C-activating G protein-coupled receptor signaling pathway
positive regulation of Rho protein signal transduction
blastocyst hatching	IEA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

multicellular organismal process [inference]

organism emergence from protective structure [inference]

hatching [inference]

blastocyst hatching

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction [inference]

positive regulation of Rho protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

regulation of Rho protein signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of Ras protein signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction [inference]

positive regulation of Rho protein signal transduction

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction [inference]

positive regulation of Rho protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

regulation of Rho protein signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of Ras protein signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction [inference]

positive regulation of Rho protein signal transduction

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction [inference]

positive regulation of Rho protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

regulation of Rho protein signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of Ras protein signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction [inference]

positive regulation of Rho protein signal transduction

Displaying **all 2** entries
GO Term	Evidence Code	PMID
intracellular membrane-bounded organelle	IDA
plasma membrane	IBA IDA TAS	18297070

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

intracellular organelle [inference]

intracellular membrane-bounded organelle

Displaying **all 2** entries
GO Term	Evidence Code	PMID
lysophosphatidic acid receptor activity	IBA
protein binding	IPI	32296183

GO Hierarchy

molecular function

binding [inference]

protein binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

bioactive lipid receptor activity [inference]

lysophosphatidic acid receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0110705	hypotrichosis 8	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **104** in total

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Species	Gene ID	Alliance of Genome Resources
Caenorhabditis elegans	2149	WB:WBGene00016570
Caenorhabditis elegans	2150	WB:WBGene00016570
Caenorhabditis elegans	2828	WB:WBGene00016570
Caenorhabditis elegans	2840	WB:WBGene00016570
Caenorhabditis elegans	2843	WB:WBGene00016570
Caenorhabditis elegans	2846	WB:WBGene00016570
Caenorhabditis elegans	2859	WB:WBGene00016570
Caenorhabditis elegans	8477	WB:WBGene00016570
Caenorhabditis elegans	9002	WB:WBGene00016570
Caenorhabditis elegans	9290	WB:WBGene00016570