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ORMDL sphingolipid biosynthesis regulator 1

Summary

Gene Symbol

ORMDL1

Organism

Anas platyrhynchos (mallard)

External Links

NCBI Gene: 101799589
KEGG Gene ID: apla:101799589
PubChem: 101799589

Annotation

Keyword

Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
R0KBM9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
ceramide metabolic process	IEA	30032202
negative regulation of ceramide biosynthetic process	IEA	30032202
intracellular sphingolipid homeostasis	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

ceramide metabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular sphingolipid homeostasis

chemical homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular sphingolipid homeostasis

lipid homeostasis [inference]

intracellular sphingolipid homeostasis

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of lipid biosynthetic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of lipid metabolic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of membrane lipid metabolic process [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of nitrogen compound metabolic process [inference]

regulation of amide metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

negative regulation of lipid metabolic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of lipid biosynthetic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of membrane lipid metabolic process [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of lipid metabolic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of membrane lipid metabolic process [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of cellular component biogenesis [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA	22301074 30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ORM1-like protein

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
ceramide metabolic process
intracellular sphingolipid homeostasis
sphingolipid biosynthetic process

Displaying 1 entry
InterPro
ORMDL family

Ortholog

Displaying entries **21 - 30** of **107** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Cavia porcellus	100716505			CAVPO01908
Cricetulus griseus	100767133			CRIGR24415
Capra hircus	100861146			CAPHI21127
Otolemur garnettii	100959497			OTOGA02545
Pan paniscus	100995457			PANPA26268
Papio anubis	101000197			PAPAN01989
Saimiri boliviensis boliviensis	101028152			SAIBB33861
Saimiri boliviensis boliviensis	101035742			SAIBB33861
Takifugu rubripes	101068288			TAKRU26329
Felis catus	101080649			FELCA20159

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024