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Repository for lectin-assisted multimodality data

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Guidelines

MIRAGE

CD44 molecule (IN blood group)

Summary

Gene Symbol

Cd44

Organism

Mesocricetus auratus (golden hamster)

External Links

NCBI Gene: 101826056
PubChem: 101826056

Annotation

Keyword

Alternative splicing
Cell adhesion
Cell membrane
Cell projection
Disulfide bond
Phosphoprotein
Proteoglycan
Receptor
Reference proteome
Secreted
Signal
Transmembrane helix

Proteins

Displaying entries **1 - 10** of 12 in total

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UniProt	Protein Name
A0A3Q0CYZ5	Extracellular matrix receptor III GP90 lymphocyte homing/adhesion receptor HUTCH-I Hermes antigen Hyaluronate receptor Phagocytic glycoprotein 1 Phagocytic glycoprotein I
A0A1U8CBK2	Extracellular matrix receptor III GP90 lymphocyte homing/adhesion receptor HUTCH-I Hermes antigen Hyaluronate receptor Phagocytic glycoprotein 1 Phagocytic glycoprotein I
Q60522	Extracellular matrix receptor III GP90 lymphocyte homing/adhesion receptor HAM1 antigen HUTCH-I Heparan sulfate proteoglycan Hermes antigen Hyaluronate receptor Phagocytic glycoprotein 1 Phagocytic glycoprotein I
A0A1U7Q2F4	Extracellular matrix receptor III GP90 lymphocyte homing/adhesion receptor HUTCH-I Hermes antigen Hyaluronate receptor Phagocytic glycoprotein 1 Phagocytic glycoprotein I
A0A3Q0CUQ2	Extracellular matrix receptor III GP90 lymphocyte homing/adhesion receptor HUTCH-I Hermes antigen Hyaluronate receptor Phagocytic glycoprotein 1 Phagocytic glycoprotein I
A0A3Q0D0N1	Extracellular matrix receptor III GP90 lymphocyte homing/adhesion receptor HUTCH-I Hermes antigen Hyaluronate receptor Phagocytic glycoprotein 1 Phagocytic glycoprotein I
A0ABM2XD97	Extracellular matrix receptor III GP90 lymphocyte homing/adhesion receptor HUTCH-I Hermes antigen Hyaluronate receptor Phagocytic glycoprotein 1 Phagocytic glycoprotein I
A0A1U8C140	Extracellular matrix receptor III GP90 lymphocyte homing/adhesion receptor HUTCH-I Hermes antigen Hyaluronate receptor Phagocytic glycoprotein 1 Phagocytic glycoprotein I
A0A3Q0CUI7	Extracellular matrix receptor III GP90 lymphocyte homing/adhesion receptor HUTCH-I Hermes antigen Hyaluronate receptor Phagocytic glycoprotein 1 Phagocytic glycoprotein I
A0A1U7Q3B6	Extracellular matrix receptor III GP90 lymphocyte homing/adhesion receptor HUTCH-I Hermes antigen Hyaluronate receptor Phagocytic glycoprotein 1 Phagocytic glycoprotein I

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
inflammatory response	IEA	30032202
cell adhesion	IEA	22301074 30032202
wound healing, spreading of cells
positive regulation of ERK1 and ERK2 cascade	IEA	30032202
regulation of lamellipodium morphogenesis

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

cell motility [inference]

cell migration [inference]

wound healing, spreading of cells

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of lamellipodium morphogenesis

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

regulation of plasma membrane bounded cell projection organization [inference]

regulation of lamellipodium organization [inference]

regulation of lamellipodium morphogenesis

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
extracellular region
plasma membrane	IEA	30032202
microvillus
basolateral plasma membrane	IEA	30032202
apical plasma membrane

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

macrophage migration inhibitory factor receptor complex

cellular anatomical entity [inference]

extracellular region

membrane [inference]

plasma membrane

plasma membrane region [inference]

cell projection membrane [inference]

lamellipodium membrane

leading edge membrane [inference]

lamellipodium membrane

cell projection

plasma membrane bounded cell projection [inference]

actin-based cell projection [inference]

microvillus

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cytokine receptor activity	IEA	30032202
hyaluronic acid binding	IEA	22301074 30032202

GO Hierarchy

molecular function

binding [inference]

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

hyaluronic acid binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity

immune receptor activity [inference]

cytokine receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

cd44 antigen

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
hyaluronic acid binding
inflammatory response
positive regulation of ERK1 and ERK2 cascade

Displaying **all 5** entries
InterPro
C-type lectin fold
C-type lectin-like/link domain superfamily
CD44 antigen-like
CD44 antigen
Link domain

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026