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N-glycanase 1

Summary

Gene Symbol

NGLY1

Organism

Macaca fascicularis (crab-eating macaque)

External Links

NCBI Gene: 101925902
KEGG Gene ID: mcf:101925902
PubChem: 101925902

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein quality control for misfolded or incompletely synthesized proteins	IEA	30032202
glycoprotein catabolic process	IEA	22301074 30032202
protein deglycosylation	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

protein quality control for misfolded or incompletely synthesized proteins

glycoprotein metabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

protein modification process [inference]

protein deglycosylation

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

carbohydrate derivative catabolic process [inference]

glycoprotein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

protein quality control for misfolded or incompletely synthesized proteins

glycoprotein metabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

protein modification process [inference]

protein deglycosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

protein quality control for misfolded or incompletely synthesized proteins

glycoprotein metabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

protein modification process [inference]

protein deglycosylation

macromolecule modification [inference]

protein modification process [inference]

protein deglycosylation

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

carbohydrate derivative catabolic process [inference]

glycoprotein catabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

protein quality control for misfolded or incompletely synthesized proteins

glycoprotein metabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

protein modification process [inference]

protein deglycosylation

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

carbohydrate derivative catabolic process [inference]

glycoprotein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
nucleus	IEA	30032202
cytoplasm	IEA	22301074
cytosol	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying 1 entry
GO Term	Evidence Code	PMID
peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [inference]

peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

peptide-n(4)-(n-acetyl-beta-glucosaminyl) asparagine amidase

Functional Category

C: Energy production and conversion
L: Replication, recombination and repair
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 4** entries
Gene Ontology
glycoprotein catabolic process
metal ion binding
peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity
protein quality control for misfolded or incompletely synthesized proteins

Displaying **all 2** entries
InterPro
Papain-like cysteine peptidase superfamily
Transglutaminase-like

KEGG BRITE Database

Orthology

K01456

Name

peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase [EC:3.5.1.52]

References

Ortholog

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	55768	HUMAN68931
Mus musculus	59007	MOUSE14771
Rattus norvegicus	361014	RATNO10579
Pan troglodytes	460233	PANTR30628
Bos taurus	533736	BOVIN22204
Danio rerio	553627	DANRE16239
Macaca mulatta	700842	MACMU30156
Monodelphis domestica	100031666	MONDO33847
Equus caballus	100059456	HORSE11226
Ornithorhynchus anatinus	100075786	ORNAN25925