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potassium two pore domain channel subfamily K member 1

Summary

Gene Symbol

Kcnk1

Organism

Ictidomys tridecemlineatus (thirteen-lined ground squirrel)

External Links

NCBI Gene: 101967151
PubChem: 101967151

Annotation

Keyword

Cell membrane
Cell projection
Cytoplasmic vesicle
Disulfide bond
Endosome
Glycoprotein
Isopeptide bond
Potassium channel
Reference proteome
Synapse
Transmembrane helix
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
I3LY61

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
glutamate secretion
stabilization of membrane potential	IEA	30032202
regulation of resting membrane potential
potassium ion transmembrane transport	IEA	22301074 30032202
chloride transmembrane transport

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic cation transmembrane transport [inference]

potassium ion transmembrane transport

export from cell [inference]

secretion by cell [inference]

glutamate secretion

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

potassium ion transport [inference]

potassium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

monoatomic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

inorganic anion transmembrane transport [inference]

chloride transmembrane transport

secretion [inference]

secretion by cell [inference]

glutamate secretion

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic cation transmembrane transport [inference]

potassium ion transmembrane transport

organic substance transport [inference]

organic anion transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

glutamate secretion

amino acid transport [inference]

acidic amino acid transport [inference]

glutamate secretion

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

glutamate secretion

amino acid transport [inference]

acidic amino acid transport [inference]

glutamate secretion

nitrogen compound transport [inference]

amino acid transport [inference]

acidic amino acid transport [inference]

glutamate secretion

amide transport [inference]

glutamate secretion

export from cell [inference]

secretion by cell [inference]

glutamate secretion

biological regulation [inference]

regulation of biological quality [inference]

regulation of membrane potential [inference]

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
membrane	IEA	22301074 30032202
dendrite
perikaryon
recycling endosome
synaptic membrane

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

voltage-gated potassium channel complex [inference]

inward rectifier potassium channel complex

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

potassium channel complex [inference]

voltage-gated potassium channel complex [inference]

inward rectifier potassium channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

potassium channel complex [inference]

voltage-gated potassium channel complex [inference]

inward rectifier potassium channel complex

cellular anatomical entity [inference]

membrane

plasma membrane region [inference]

synaptic membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

perikaryon

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
inward rectifier potassium channel activity
sodium channel activity
outward rectifier potassium channel activity
potassium ion leak channel activity	IEA	30032202
identical protein binding

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

monoatomic cation channel activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity [inference]

potassium ion leak channel activity

sodium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

inward rectifier potassium channel activity

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

inward rectifier potassium channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity [inference]

potassium ion leak channel activity

sodium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

inward rectifier potassium channel activity

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity [inference]

potassium ion leak channel activity

sodium ion transmembrane transporter activity [inference]

sodium channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity [inference]

potassium ion leak channel activity

sodium ion transmembrane transporter activity [inference]

sodium channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

monoatomic cation channel activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity [inference]

potassium ion leak channel activity

sodium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

inward rectifier potassium channel activity

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

inward rectifier potassium channel activity

gated channel activity [inference]

voltage-gated channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

inward rectifier potassium channel activity

narrow pore channel activity [inference]

leak channel activity [inference]

potassium ion leak channel activity

salt transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity [inference]

potassium ion leak channel activity

sodium ion transmembrane transporter activity [inference]

sodium channel activity

binding [inference]

protein binding [inference]

identical protein binding

protein dimerization activity [inference]

protein heterodimerization activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

potassium channel subfamily k member

Functional Category

E: Amino acid transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
monoatomic ion transport
outward rectifier potassium channel activity
potassium channel activity
potassium ion leak channel activity
stabilization of membrane potential

Displaying **all 5** entries
InterPro
Potassium channel domain
Two pore domain potassium channel, TASK family
Two pore domain potassium channel, TWIK family
Two pore domain potassium channel, TWIK-1
Two pore domain potassium channel

Ortholog

Displaying entries **41 - 50** of 73 in total

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Species	Gene ID	Orthologous MAtrix
Chlorocebus sabaeus	103230773	CHLSB12311
Serinus canaria	103818514	SERCA14069
Rhinopithecus roxellana	104678314	RHIRO25221
Macaca nemestrina	105464119	MACNE43576
Mandrillus leucophaeus	105546242	MANLE25537
Cercocebus atys	105574868	CERAT14188
Propithecus coquereli	105823089	PROCO05420
Dipodomys ordii	105984447	DIPOR05651
Equus asinus asinus	106839692	EQUAS28305
Sinocyclocheilus grahami	107553189	SINGR39703