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Standards Ontologies Notations
fatty acid synthase

Summary
Gene Symbol
  • FASN
Organism
Geospiza fortis (medium ground-finch)
NCBI Gene
102043163
KEGG Gene ID
gfr:102043163
PubChem
102043163
Annotation
Keyword
  • Acetylation
  • Fatty acid biosynthesis
  • Hydrolase
  • Lyase
  • Multifunctional enzyme
  • NAD
  • NADP
  • Phosphopantetheine
  • Phosphoprotein
  • Pyridoxal phosphate
  • Reference proteome
  • S-nitrosylation
  • Transferase
Proteins
Displaying 1 entry
UniProt Protein Name
A0A6I9HS68
Annotation information from UniProt.
Gene Ontology (GO)
Displaying 1 entry
GO Term Evidence Code PMID
fatty acid biosynthetic process
GO Hierarchy
Displaying 1 entry
GO Term Evidence Code PMID
cytoplasm
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
3-ketoacyl-coa synthase
Functional Category
  • I: Lipid transport and metabolism
  • Q: Secondary metabolites biosynthesis, transport and catabolism
  • T: Signal transduction mechanisms
Displaying all 3 entries
Gene Ontology
fatty acid synthase activity
secondary metabolite biosynthetic process
transferase activity
Displaying all 7 entries
InterPro
ACP-like superfamily
Acyl transferase domain superfamily
Beta-ketoacyl synthase, C-terminal
Beta-ketoacyl synthase, N-terminal
Phosphopantetheine binding ACP domain
Polyketide synthase, beta-ketoacyl synthase domain
Thiolase-like
KEGG BRITE Database
Orthology
K00665
Name
fatty acid synthase, animal type [EC:2.3.1.85]
References
Rhea

RHEA:22564

NADP+
H+ + NADPH
Enzyme
PMID

RHEA:41792

malonyl-CoA
CoA
Enzyme
PMID

RHEA:41788

acetyl-CoA
CoA
Enzyme
PMID

RHEA:41932

H2O
H+ + hexadecanoate
Enzyme
PMID

RHEA:15057

H2O
H+ + (9Z)-octadecenoate
Enzyme
PMID

RHEA:14993

H+ + acetyl-CoA + malonyl-CoA + NADPH
CO2 + CoA + a long-chain fatty acid + NADP+
Enzyme
PMID

RHEA:30123

H2O
H+ + tetradecanoate
Enzyme
PMID

RHEA:22836

H+
CO2
Enzyme
PMID

RHEA:17397

NADP+
H+ + NADPH
Enzyme
PMID
Ortholog
Displaying entries 21 - 30 of 44 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
116796068 296741_0:002d76
117005216 91951_0:002edf
117005224 91951_0:002fa0
118693765 84834_0:002d0e
119709366 1094192_0:002b9e
120505406 9160_0:002236
120761148 43150_0:002ae3
121338244 356909_0:001e79
121352757 221976_0:001525
121663430 68294_0:001148
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024