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Guidelines

MIRAGE

transmembrane O-mannosyltransferase targeting cadherins 4

Summary

Gene Symbol

TMTC4

Organism

Macaca fascicularis (crab-eating macaque)

External Links

NCBI Gene: 102132988
KEGG Gene ID: mcf:102132988
PubChem: 102132988

Annotation

Keyword

Reference proteome
Repeat
TPR repeat
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A2K5VJM6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum unfolded protein response	IEA	30032202
protein O-linked mannosylation	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

mannosylation [inference]

protein mannosylation [inference]

protein O-linked mannosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

cellular process [inference]

signal transduction [inference]

endoplasmic reticulum unfolded protein response

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

endoplasmic reticulum unfolded protein response

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 2** entries
GO Term	Evidence Code	PMID
mannosyltransferase activity	IEA	30032202
protein binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

mannosyltransferase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Cercopithecoidea

Group Name

protein O-mannosyl-transferase TMTC4 isoform X1

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
dolichyl-phosphate-mannose-protein mannosyltransferase activity
endoplasmic reticulum unfolded protein response
mannosyltransferase activity
protein O-linked mannosylation

KEGG BRITE Database

Orthology

K23424

Name

protein O-mannosyl-transferase [EC:2.4.1.-]

References

28973932

Ortholog

Displaying entries **11 - 20** of 87 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Taeniopygia guttata	100223748		TAEGU10716
Oryctolagus cuniculus	100358355		RABIT12556
Callithrix jacchus	100414694		CALJA20242
Pongo abelii	100458592		PONAB06644
Ailuropoda melanoleuca	100472654		AILME17226
Sus scrofa	100524643		PIGXX01479
Anolis carolinensis	100567128		ANOCA04544
Nomascus leucogenys	100591884		NOMLE30830
Oreochromis niloticus	100691018		ORENI22222
Cavia porcellus	100722385		CAVPO02416

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.2.0

Last updated: March 31, 2025