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oxoglutarate dehydrogenase

Summary

Gene Symbol

OGDH

Organism

Capra hircus (goat)

External Links

NCBI Gene: 102183291
KEGG Gene ID: chx:102183291
PubChem: 102183291

Annotation

Keyword

Isopeptide bond
Nucleus
Oxidoreductase
Reference proteome
Thiamine pyrophosphate
Transit peptide
Ubl conjugation

Proteins

Displaying **all 4** entries
UniProt	Protein Name
A0A452DTL0	2-oxoglutarate dehydrogenase, mitochondrial Alpha-ketoglutarate dehydrogenase Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase
A0A452DTJ5	2-oxoglutarate dehydrogenase, mitochondrial Alpha-ketoglutarate dehydrogenase Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase
A0A452DTF2	2-oxoglutarate dehydrogenase, mitochondrial Alpha-ketoglutarate dehydrogenase Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase
A0A452DTD2	2-oxoglutarate dehydrogenase, mitochondrial Alpha-ketoglutarate dehydrogenase Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
tricarboxylic acid cycle	IEA	22301074 30032202

GO Hierarchy

biological process

metabolic process [inference]

primary metabolic process [inference]

tricarboxylic acid cycle

Displaying **all 2** entries
GO Term	Evidence Code	PMID
oxoglutarate dehydrogenase complex	IEA	30032202
mitochondrion	IEA	30032202

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

tricarboxylic acid cycle enzyme complex [inference]

dihydrolipoyl dehydrogenase complex [inference]

oxoglutarate dehydrogenase complex

oxidoreductase complex [inference]

dihydrolipoyl dehydrogenase complex [inference]

oxoglutarate dehydrogenase complex

transferase complex [inference]

oxoglutarate dehydrogenase complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 2** entries
GO Term	Evidence Code	PMID
oxoglutarate dehydrogenase (succinyl-transferring) activity	IEA	22301074 30032202
thiamine pyrophosphate binding	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor [inference]

oxoglutarate dehydrogenase (succinyl-transferring) activity

binding [inference]

small molecule binding [inference]

vitamin binding [inference]

thiamine pyrophosphate binding

quaternary ammonium group binding [inference]

thiamine pyrophosphate binding

heterocyclic compound binding [inference]

thiamine pyrophosphate binding

ion binding [inference]

anion binding [inference]

thiamine pyrophosphate binding

cation binding [inference]

thiamine pyrophosphate binding

organic cyclic compound binding [inference]

thiamine pyrophosphate binding

sulfur compound binding [inference]

thiamine pyrophosphate binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00164

Name

2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]

References

Rhea

RHEA:12188

H⁺ + 2-oxoglutarate

CO₂

Enzyme

1.2.4.2

PMID

Ortholog

Displaying entries **51 - 60** of **105** in total

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Species	Gene ID	Orthologous MAtrix
Bos taurus	132342072	BOVIN28240
Ovis aries	101115360	SHEEP15601
Oryctolagus cuniculus	100359048	RABIT01735
Dipodomys ordii	105998289	DIPOR20623
Cricetulus griseus	100764862	CRIGR13193
Mus musculus	18293	MOUSE06917
Rattus norvegicus	360975	RATNO08896
Cavia porcellus	100724083	CAVPO18932
Octodon degus	101574618	OCTDE08821
Heterocephalus glaber	101716205	HETGA08828

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Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements