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catechol-O-methyltransferase

Summary

Gene Symbol

COMT

Organism

Capra hircus (goat)

External Links

NCBI Gene: 102191825
KEGG Gene ID: chx:102191825
PubChem: 102191825

Annotation

Keyword

Catecholamine metabolism
Magnesium
Metal-binding
Methyltransferase
Neurotransmitter degradation
Reference proteome
S-adenosyl-L-methionine
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A452DTI0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
catecholamine catabolic process	IEA	30032202
developmental process	IEA	30032202
dopamine metabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process [inference]

catecholamine metabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process

organonitrogen compound catabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process

catabolic process [inference]

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organonitrogen compound catabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process

organic hydroxy compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

aromatic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organic substance metabolic process [inference]

organic cyclic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organic cyclic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organonitrogen compound metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process [inference]

catecholamine metabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process

organonitrogen compound catabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organonitrogen compound catabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process

organic hydroxy compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organic hydroxy compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organic hydroxy compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

aromatic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

developmental process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
axon	IEA	30032202
dendrite	IEA	30032202
membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
magnesium ion binding	IEA	22301074
catechol O-methyltransferase activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring one-carbon groups [inference]

methyltransferase activity [inference]

O-methyltransferase activity [inference]

catechol O-methyltransferase activity

S-adenosylmethionine-dependent methyltransferase activity [inference]

catechol O-methyltransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

magnesium ion binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00545

Name

catechol O-methyltransferase [EC:2.1.1.6]

References

Rhea

a catechol + S-adenosyl-L-methionine

a guaiacol + H⁺ + S-adenosyl-L-homocysteine

Enzyme

2.1.1.6

PMID

Ortholog

Displaying entries **21 - 30** of 70 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Erinaceus europaeus	103123291		ERIEU02845
Macaca mulatta	712548		MACMU00872
Papio anubis	101022593		PAPAN12086
Pan troglodytes	458655		PANTR25982
Homo sapiens	1312		HUMAN59230
Canis lupus familiaris	445450		CANLF10595
Vulpes vulpes	112907521		VULVU33181
Ailuropoda melanoleuca	100473702		AILME11410
Mustela putorius furo	101691541		MUSPF17595
Felis catus	101097022		FELCA28433

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.0.0

Last updated: August 19, 2024