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ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2)
Summary
- Gene Symbol
-
- adamts5
- Organism
- Xiphophorus maculatus (southern platyfish)
Annotation
- Keyword
-
- Calcium
- Cleavage on pair of basic residues
- Disulfide bond
- Glycoprotein
- Metal-binding
- Metalloprotease
- Reference proteome
- Secreted
- Signal
- Zinc
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A3B5R6E4 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| extracellular matrix organization |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region |
|
|
| collagen-containing extracellular matrix |
| GO Term | Evidence Code | PMID |
|---|---|---|
| metalloendopeptidase activity | ||
| zinc ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- A disintegrin and metalloproteinase with thrombospondin motifs
- Functional Category
-
- I: Lipid transport and metabolism
- K: Transcription
- Q: Secondary metabolites biosynthesis, transport and catabolism
| Gene Ontology |
|---|
| extracellular matrix organization |
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 11096 | HUMAN58164 | ||
| 23794 | MOUSE18736 | ||
| 286805 | BOVIN14254 | ||
| 304135 | RATNO04830 | ||
| 473935 | PANTR25477 | ||
| 565053 | DANRE18494 | ||
| 707672 | MACMU32262 | ||
| 100008799 | RABIT04960 | ||
| 100021415 | MONDO22301 | ||
| 100066005 | HORSE25010 |
