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MIRAGE
RAS guanyl releasing protein 2
Summary
- Gene Symbol
-
- RASGRP2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Calcium
- Cell membrane
- Cell projection
- Cytoplasm
- Disease variant
- Guanine-nucleotide releasing factor
- Metal-binding
- Phosphoprotein
- Reference proteome
- Repeat
- Synaptosome
- Zinc
- Zinc-finger
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of cell growth | ||
| signal transduction | ||
| Ras protein signal transduction | ||
| Ras protein signal transduction | ||
| positive regulation of GTPase activity |
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytosol | ||
| cytosol | ||
| plasma membrane | ||
| plasma membrane | ||
| ruffle membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| guanyl-nucleotide exchange factor activity | ||
| guanyl-nucleotide exchange factor activity | ||
| guanyl-nucleotide exchange factor activity | ||
| calcium ion binding | ||
| calcium ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- ras GEF
- Functional Category
-
- E: Amino acid transport and metabolism
- F: Nucleotide transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| Ras protein signal transduction |
| small GTPase-mediated signal transduction |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0111051 | platelet-type bleeding disorder 18 |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 5900 | SGD:S000000634 | ||
| 5923 | SGD:S000000634 | ||
| 5924 | SGD:S000000634 | ||
| 10235 | Xenbase:XB-GENE-6256357 | ||
| 19395 | MOUSE25528 | ||
| 19417 | SGD:S000000634 | ||
| 19418 | SGD:S000000634 | ||
| 115727 | SGD:S000000634 | ||
| 361714 | RATNO19654 | ||
| 451298 | PANTR03313 |
