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MIRAGE

oxoglutarate dehydrogenase

Summary

Gene Symbol

OGDH

Organism

Bubalus bubalis (water buffalo)

External Links

NCBI Gene: 102392279
KEGG Gene ID: bbub:102392279
PubChem: 102392279

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
tricarboxylic acid cycle	IEA	22301074 30032202

GO Hierarchy

biological process

metabolic process [inference]

primary metabolic process [inference]

tricarboxylic acid cycle

Displaying **all 2** entries
GO Term	Evidence Code	PMID
mitochondrion	IEA	30032202
oxoglutarate dehydrogenase complex	IEA	30032202

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

tricarboxylic acid cycle enzyme complex [inference]

dihydrolipoyl dehydrogenase complex [inference]

oxoglutarate dehydrogenase complex

oxidoreductase complex [inference]

dihydrolipoyl dehydrogenase complex [inference]

oxoglutarate dehydrogenase complex

transferase complex [inference]

oxoglutarate dehydrogenase complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 2** entries
GO Term	Evidence Code	PMID
oxoglutarate dehydrogenase (succinyl-transferring) activity	IEA	22301074 30032202
thiamine pyrophosphate binding	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor [inference]

oxoglutarate dehydrogenase (succinyl-transferring) activity

binding [inference]

small molecule binding [inference]

vitamin binding [inference]

thiamine pyrophosphate binding

quaternary ammonium group binding [inference]

thiamine pyrophosphate binding

heterocyclic compound binding [inference]

thiamine pyrophosphate binding

ion binding [inference]

anion binding [inference]

thiamine pyrophosphate binding

cation binding [inference]

thiamine pyrophosphate binding

organic cyclic compound binding [inference]

thiamine pyrophosphate binding

sulfur compound binding [inference]

thiamine pyrophosphate binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

oxoglutarate dehydrogenase

Functional Category

C: Energy production and conversion
G: Carbohydrate transport and metabolism
H: Coenzyme transport and metabolism
I: Lipid transport and metabolism

Displaying **all 5** entries
Gene Ontology
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
oxidoreductase activity
oxoglutarate dehydrogenase (succinyl-transferring) activity
thiamine pyrophosphate binding
tricarboxylic acid cycle

Displaying **all 6** entries
InterPro
2-oxoglutarate dehydrogenase E1 component
Dehydrogenase, E1 component
Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily
Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal
Thiamin diphosphate-binding fold
Transketolase-like, pyrimidine-binding domain

KEGG BRITE Database

Orthology

K00164

Name

2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]

References

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026