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alpha glucosidase

Summary

Gene Symbol

GAA

Organism

Vicugna pacos (alpaca)

External Links

NCBI Gene: 102525500
KEGG Gene ID: vpc:102525500
PubChem: 102525500

Annotation

Keyword

Disulfide bond
Glycoprotein
Glycosidase
Lysosome
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A6J0ADG7	Acid maltase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
glycogen catabolic process	IEA	30032202
lysosome organization	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

carbohydrate catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process [inference]

glycogen catabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

glucan metabolic process [inference]

glycogen metabolic process [inference]

glycogen catabolic process

glucan catabolic process [inference]

glycogen catabolic process

carbohydrate catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

glucan metabolic process [inference]

glycogen metabolic process [inference]

glycogen catabolic process

glucan catabolic process [inference]

glycogen catabolic process

carbohydrate catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

glucan metabolic process [inference]

glycogen metabolic process [inference]

glycogen catabolic process

glucan catabolic process [inference]

glycogen catabolic process

macromolecule catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

carbohydrate catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

cellular process [inference]

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process [inference]

glycogen catabolic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vacuole organization [inference]

lytic vacuole organization [inference]

lysosome organization

Displaying 1 entry
GO Term	Evidence Code	PMID
lysosomal membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
alpha-1,4-glucosidase activity	IEA	30032202
carbohydrate binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

glucosidase activity [inference]

alpha-glucosidase activity [inference]

alpha-1,4-glucosidase activity

binding [inference]

carbohydrate binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Artiodactyla

Group Name

lysosomal alpha-glucosidase

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
alpha-glucosidase activity
catalytic activity
glycogen catabolic process
hydrolase activity, acting on glycosyl bonds
hydrolase activity
lysosome organization

Displaying entries **1 - 10** of 11 in total

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2

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InterPro
Galactose mutarotase-like domain superfamily
Glycoside hydrolase family 31, N-terminal domain
Glycoside hydrolase family 31, TIM barrel domain
Glycoside hydrolase superfamily
Glycosyl hydrolase family 31, C-terminal domain
Glycosyl hydrolase, all-beta
Glycosyl hydrolases family 31, active site
Glycosyl hydrolases family 31, conserved site
P-type trefoil domain superfamily
P-type trefoil domain

KEGG BRITE Database

Orthology

K12316

Name

lysosomal alpha-glucosidase [EC:3.2.1.20]

References

Ortholog

Displaying entries **11 - 20** of 24 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Camelus bactrianus	105065582	9837_0:001563
Camelus dromedarius	105106261	9838_0:002a91
Bos indicus	109574062	9915_0:0038c3
Bos indicus x Bos taurus	113877724	30522_0:00377c
Monodon monoceros	114889147	40151_0:0047e9
Balaenoptera musculus	118886936	9771_0:004561
Oryx dammah	120866837	59534_0:00142b
Cervus canadensis	122438124	1574408_0:0001ba
Cervus elaphus	122695427	9860_0:0011da
Phacochoerus africanus	125114145	41426_0:00416b

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.1.0

Last updated: December 9, 2024