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plastin 3 (T-isoform)

Summary

Gene Symbol

Pls3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

102866

PubChem

102866

Alliance of Genome Resources

MGI:104807

Annotation

Keyword

Actin-binding
Calcium
Cytoplasm
Direct protein sequencing
Metal-binding
Phosphoprotein
Proteomics identification
Reference proteome
Repeat

Proteins

Displaying **all 4** entries
UniProt	Protein Name
Q3UKB1	T-plastin
Q99K51	T-plastin
Q3UJG9	T-plastin
B1AX58	T-plastin

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
actin filament bundle assembly	IBA
actin filament bundle assembly	IEA
actin filament network formation	IBA
bone development	ISO
regulation of synaptic vesicle cycle	IDA	23263861

GO Hierarchy

biological process

cellular process [inference]

actin filament-based process [inference]

actin cytoskeleton organization [inference]

presynaptic actin cytoskeleton organization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization [inference]

presynaptic actin cytoskeleton organization

presynaptic cytoskeleton organization [inference]

presynaptic actin cytoskeleton organization

cellular component assembly [inference]

actin filament bundle assembly

supramolecular fiber organization [inference]

actin filament organization [inference]

actin filament network formation

actin filament bundle organization [inference]

actin filament bundle assembly

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

bone development

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of vesicle-mediated transport [inference]

regulation of synaptic vesicle cycle

regulation of cellular process [inference]

regulation of vesicle-mediated transport [inference]

regulation of synaptic vesicle cycle

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GO Term	Evidence Code	PMID
cytoplasm	IDA	7655078
cytoplasm	IBA
cytosol	ISO
actin filament	IBA
plasma membrane	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell junction [inference]

synapse [inference]

neuromuscular junction

actin filament bundle

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

stereocilium

actin-based cell projection [inference]

stereocilium

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

actin filament

Displaying **all 5** entries
GO Term	Evidence Code	PMID
calcium ion binding	IEA
actin filament binding	IBA
actin filament binding	IEA
structural constituent of presynaptic actin cytoskeleton	IDA	23263861
structural constituent of presynaptic actin cytoskeleton	IMP	23263861

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of cytoskeleton [inference]

structural constituent of presynaptic actin cytoskeleton

structural constituent of synapse [inference]

structural constituent of presynapse [inference]

structural constituent of presynaptic actin cytoskeleton

binding [inference]

protein binding [inference]

cytoskeletal protein binding [inference]

actin binding [inference]

actin filament binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

protein-containing complex binding [inference]

actin filament binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

fimbrin

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
actin binding
actin filament binding
actin filament network formation

Displaying **all 4** entries
InterPro
Actinin-type actin-binding domain, conserved site
CH domain superfamily
Calponin homology domain
Fimbrin/Plastin

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:11476	osteoporosis	Alliance of Genome Resources
DOID:3827	congenital diaphragmatic hernia	Alliance of Genome Resources

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	3936	SGD:S000002536
Saccharomyces cerevisiae S288C	5357	SGD:S000002536
Homo sapiens	5358	Xenbase:XB-GENE-922728	HUMAN101931
Rattus norvegicus	81748		RATNO45238
Xenopus tropicalis	102866	Xenbase:XB-GENE-922728
Danio rerio	436598		DANRE07075
Pan troglodytes	465817		PANTR46640
Canis lupus familiaris	481025		CANLF20079
Bos taurus	505687		BOVIN36780
Macaca mulatta	709055		MACMU47254

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements