GlyCosmos Portal

GlyTouCan

Glycan Structure Repository

GlyComb

Glycoconjugate Repository

GlycoPOST

Glycomics MS raw data Repository

UniCarb-DR

Glycomics MS Repository for glycan annotations from GlycoWorkbench

All Resources

Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms

Other Information

Release Statistics Download

Tools

Glycan Converters

LM-GlycomeAtlas

Search Tools

Cross Search Glycan Search Publication Search Programmatic Access

thromboxane A synthase 1

Summary

Gene Symbol

TBXAS1

Organism

Panthera tigris (tiger)

External Links

NCBI Gene: 102970130
KEGG Gene ID: ptg:102970130
PubChem: 102970130

Annotation

Keyword

Endoplasmic reticulum
Heme
Isomerase
Membrane
Monooxygenase
Prostaglandin biosynthesis
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A8C9KCU7	Cytochrome P450 5A1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA	22301074
thromboxane-A synthase activity	IEA	30032202
monooxygenase activity	IEA	22301074
iron ion binding	IEA	22301074
heme binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

isomerase activity [inference]

intramolecular oxidoreductase activity [inference]

thromboxane-A synthase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

organic cyclic compound binding [inference]

tetrapyrrole binding [inference]

heme binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K01832

Name

thromboxane-A synthase [EC:5.3.99.5]

References

1714723

Rhea

a hydroperoxyeicosatetraenoate

an oxoeicosatetraenoate + H₂O

Enzyme

4.2.1.152

PMID

(12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate

H₂O + 12-oxo-(5Z,8Z,10E,14Z)-eicosatetraenoate

Enzyme

4.2.1.152

PMID

12881489

(8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate

H₂O + 8-oxo-(5Z,9E,11Z,14Z)-eicosatetraenoate

Enzyme

4.2.1.152

PMID

17045234

prostaglandin H₂

thromboxane A₂

Enzyme

5.3.99.5

PMID

(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate

H₂O + 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate

Enzyme

4.2.1.152

PMID

(8R)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate

H₂O + 8-oxo-(5Z,9E,11Z,14Z)-eicosatetraenoate

Enzyme

4.2.1.152

PMID

17045234

(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate

H₂O + 12-oxo-(5Z,8Z,10E,14Z)-eicosatetraenoate

Enzyme

4.2.1.152

PMID

12881489

About Release Notes Help Feedback

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: support@glycosmos.org

GlyCosmos Portal v4.0.0

Last updated: August 19, 2024