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N-deacetylase and N-sulfotransferase 2

Summary

Gene Symbol

NDST2

Organism

Physeter catodon (sperm whale)

External Links

NCBI Gene: 102973206
KEGG Gene ID: pcad:102973206
PubChem: 102973206

Annotation

Keyword

Disulfide bond
Hydrolase
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A2Y9F596

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
Golgi apparatus	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying **all 2** entries
GO Term	Evidence Code	PMID
deacetylase activity	IEA	30032202
[heparan sulfate]-glucosamine N-sulfotransferase activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring sulphur-containing groups [inference]

sulfotransferase activity [inference]

heparan sulfate sulfotransferase activity [inference]

[heparan sulfate]-glucosamine N-sulfotransferase activity

hydrolase activity [inference]

deacetylase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

bifunctional heparan sulfate n-deacetylase/n-sulfotransferase

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 6** entries
Gene Ontology
deacetylase activity
heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
heparan sulfate proteoglycan biosynthetic process
heparin biosynthetic process
hydrolase activity
sulfotransferase activity

Displaying **all 4** entries
InterPro
Heparan sulfate sulfotransferase
Heparan sulphate-N-deacetylase
P-loop containing nucleoside triphosphate hydrolase
Sulfotransferase domain

KEGG BRITE Database

Orthology

K02577

Name

heparan sulfate N-deacetylase/N-sulfotransferase NDST2 [EC:3.5.1.- 2.8.2.8]

References

Rhea

3'-phosphoadenylyl sulfate

H⁺ + adenosine 3',5'-bisphosphate

Enzyme

2.8.2.8

PMID

Ortholog

Displaying entries **1 - 10** of 11 in total

1

2

Next ›

Last »
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Orcinus orca	101283750	9733_0:0033ca
Tursiops truncatus	101315985	9739_0:00391d
Balaenoptera acutorostrata	103006232	9767_0:003dc7
Lipotes vexillifer	103069336	118797_0:003a4f
Delphinapterus leucas	111183529	9749_0:003215
Neophocaena asiaeorientalis asiaeorientalis	112396784	1706337_0:00014f
Lagenorhynchus obliquidens	113632579	90247_0:0028ed
Monodon monoceros	114908762	40151_0:0036fa
Phocoena sinus	116741277	42100_1:003a1a
Balaenoptera musculus	118882502	9771_0:003ad6

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024