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4-hydroxy-2-oxoglutarate aldolase 1

Summary
Gene Symbol
  • HOGA1
Organism
Physeter catodon (sperm whale)
NCBI Gene
102979032
KEGG Gene ID
pcad:102979032
PubChem
102979032
Annotation
Keyword
  • Lyase
  • Mitochondrion
  • Reference proteome
  • Schiff base
  • Transit peptide
  • Transmembrane helix
Proteins
Displaying entries 1 - 10 of 18 in total
UniProt Protein Name
A0A455AWL2
  • Dihydrodipicolinate synthase-like
  • Probable 2-keto-4-hydroxyglutarate aldolase
A0A455AVQ0
  • Dihydrodipicolinate synthase-like
  • Probable 2-keto-4-hydroxyglutarate aldolase
A0A455B8D5
  • Dihydrodipicolinate synthase-like
  • Probable 2-keto-4-hydroxyglutarate aldolase
A0A2Y9FMX7
  • Dihydrodipicolinate synthase-like
  • Probable 2-keto-4-hydroxyglutarate aldolase
A0A455AUN7
  • Dihydrodipicolinate synthase-like
  • Probable 2-keto-4-hydroxyglutarate aldolase
A0A455AVR5
  • Dihydrodipicolinate synthase-like
  • Probable 2-keto-4-hydroxyglutarate aldolase
A0A455AUD7
  • Dihydrodipicolinate synthase-like
  • Probable 2-keto-4-hydroxyglutarate aldolase
A0A455AUF2
  • Dihydrodipicolinate synthase-like
  • Probable 2-keto-4-hydroxyglutarate aldolase
A0A455B8F0
  • Dihydrodipicolinate synthase-like
  • Probable 2-keto-4-hydroxyglutarate aldolase
A0A455AUE7
  • Dihydrodipicolinate synthase-like
  • Probable 2-keto-4-hydroxyglutarate aldolase
Annotation information from UniProt.
Gene Ontology (GO)
Displaying 1 entry
GO Term Evidence Code PMID
glyoxylate catabolic process
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
4-hydroxy-2-oxoglutarate aldolase
Functional Category
  • E: Amino acid transport and metabolism
  • G: Carbohydrate transport and metabolism
  • M: Cell wall/membrane/envelope biogenesis
  • Q: Secondary metabolites biosynthesis, transport and catabolism
Displaying all 2 entries
Gene Ontology
4-hydroxy-tetrahydrodipicolinate synthase activity
lyase activity
Displaying all 2 entries
InterPro
Aldolase-type TIM barrel
DapA-like
KEGG BRITE Database
Orthology
K18123
Name
4-hydroxy-2-oxoglutarate aldolase [EC:4.1.3.16]
References
Rhea

RHEA:30687

(4R)-4-hydroxy-2-oxoglutarate
pyruvate + glyoxylate
Enzyme
PMID

RHEA:35639

(4S)-4-hydroxy-2-oxoglutarate
pyruvate + glyoxylate
Enzyme
PMID
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026