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Standards Ontologies Notations
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase

Summary
Gene Symbol
  • EHHADH
Organism
Balaenoptera acutorostrata (minke whale)
NCBI Gene
102997304
KEGG Gene ID
bacu:102997304
PubChem
102997304
Annotation
Keyword
  • Fatty acid metabolism
  • NAD
  • Peroxisome
  • Reference proteome
Proteins
Displaying all 2 entries
UniProt Protein Name
A0A384B6I4
  • Multifunctional enzyme 1
A0A384B6Q1
  • Multifunctional enzyme 1
Annotation information from UniProt.
Gene Ontology (GO)
Displaying 1 entry
GO Term Evidence Code PMID
fatty acid beta-oxidation
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Cetacea
Group Name
3-hydroxyacyl-CoA dehydrogenase, C-terminal
Functional Category
  • H: Coenzyme transport and metabolism
  • I: Lipid transport and metabolism
  • Q: Secondary metabolites biosynthesis, transport and catabolism
Displaying all 6 entries
Gene Ontology
3-hydroxyacyl-CoA dehydrogenase activity
NAD+ binding
fatty acid beta-oxidation
fatty acid metabolic process
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
oxidoreductase activity
Displaying all 7 entries
InterPro
3-hydroxyacyl-CoA dehydrogenase, C-terminal
3-hydroxyacyl-CoA dehydrogenase, NAD binding
3-hydroxyacyl-CoA dehydrogenase, conserved site
6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
ClpP/crotonase-like domain superfamily
Enoyl-CoA hydratase/isomerase
NAD(P)-binding domain superfamily
KEGG BRITE Database
Orthology
K07514
Name
enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8]
References
Rhea

RHEA:23716

(3Z)-dodecenoyl-CoA
(2E)-dodecenoyl-CoA
Enzyme
PMID

RHEA:76647

(3S)-3-hydroxyadipyl-CoA
H2O + (E)-2,3-didehydroadipoyl-CoA
Enzyme
PMID

RHEA:45900

a (3Z)-enoyl-CoA
a 4-saturated (2E)-enoyl-CoA
Enzyme
PMID

RHEA:16105

a (3S)-3-hydroxyacyl-CoA
H2O + a (2E)-enoyl-CoA
Enzyme
PMID

RHEA:45228

a (3E)-enoyl-CoA
a 4-saturated (2E)-enoyl-CoA
Enzyme
PMID

RHEA:20724

a 4-saturated-(3S)-3-hydroxyacyl-CoA
H2O + a (3E)-enoyl-CoA
Enzyme
PMID

RHEA:22432

a (3S)-3-hydroxyacyl-CoA + NAD+
H+ + NADH + a 3-oxoacyl-CoA
Enzyme
PMID
Ortholog
Displaying entries 1 - 10 of 12 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
101277611 9733_0:001649
101316998 9739_0:001345
102985760 9755_0:000104
103073756 118797_0:000f6f
111173099 9749_0:0044c4
112415146 1706337_0:0005ce
113622058 90247_0:0001de
114890570 40151_0:00082b
115855873 9731_1:0001a8
116753374 42100_1:0012e9
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024