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reticulon 3

Summary

Gene Symbol

RTN3

Organism

Homo sapiens (human)

External Links

NCBI Gene

10313

PubChem

10313

Alliance of Genome Resources

HGNC:10469

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Apoptosis
ER-Golgi transport
Endoplasmic reticulum
Golgi apparatus
Host-virus interaction
Phosphoprotein
Reference proteome
Stress response
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
O95197	Homolog of ASY protein Neuroendocrine-specific protein-like 2 Neuroendocrine-specific protein-like II

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
apoptotic process	IEA
brain development	IBA
vesicle-mediated transport	IEA
neuron differentiation	IBA
endoplasmic reticulum tubular network organization	IMP	18779370

GO Hierarchy

biological process

cellular process [inference]

cell death [inference]

programmed cell death [inference]

apoptotic process

vesicle-mediated transport

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

endoplasmic reticulum organization [inference]

endoplasmic reticulum tubular network organization

endoplasmic reticulum tubular network formation

cellular component assembly [inference]

endoplasmic reticulum tubular network formation

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

brain development

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of amyloid-beta formation

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

regulation of nitrogen compound metabolic process [inference]

regulation of amide metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of amyloid-beta formation

regulation of amyloid-beta formation [inference]

negative regulation of amyloid-beta formation

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of amyloid-beta formation

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

regulation of protein metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

regulation of amyloid precursor protein catabolic process [inference]

regulation of amyloid-beta formation [inference]

negative regulation of amyloid-beta formation

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

regulation of protein metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

regulation of amyloid precursor protein catabolic process [inference]

regulation of amyloid-beta formation [inference]

negative regulation of amyloid-beta formation

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

regulation of amyloid precursor protein catabolic process [inference]

regulation of amyloid-beta formation [inference]

negative regulation of amyloid-beta formation

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of amyloid-beta formation

negative regulation of protein metabolic process [inference]

negative regulation of amyloid precursor protein catabolic process [inference]

negative regulation of amyloid-beta formation

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
Golgi membrane	IEA
extracellular space	TAS	10331947
endoplasmic reticulum	IDA	15286784
endoplasmic reticulum membrane	IDA	24262037
endoplasmic reticulum membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

membrane [inference]

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

bounding membrane of organelle [inference]

Golgi membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

postsynaptic specialization [inference]

postsynaptic density

Displaying 1 entry
GO Term	Evidence Code	PMID
protein binding	IPI	15286784 16189514 16965550 19364499 21044950 21976701 25416956 26871637 29892012 31515488 32296183 33961781 35271311

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Reticulon

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
Reticulon 1-4
Reticulon

Ortholog

Displaying entries **11 - 20** of 54 in total

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Species	Gene ID	Orthologous MAtrix
Pan troglodytes	451281	PANTR03229
Takifugu rubripes	654271	TAKRU49039
Monodelphis domestica	100011483	MONDO26298
Ornithorhynchus anatinus	100088381	ORNAN19050
Pongo abelii	100172388	PONAB02768
Callithrix jacchus	100405288	CALJA05451
Nomascus leucogenys	100593953	NOMLE28820
Cavia porcellus	100726196	CAVPO16025
Pan paniscus	100978994	PANPA06965
Pan paniscus	100987550	PANPA06965