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phosphatidylinositol-5-phosphate 4-kinase type 2 alpha

Summary

Gene Symbol

PIP4K2A

Organism

Chlorocebus sabaeus (green monkey)

External Links

NCBI Gene: 103238000
KEGG Gene ID: csab:103238000
PubChem: 103238000

Annotation

Keyword

ATP-binding
Cell membrane
Kinase
Lysosome
Nucleus
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A0D9RJ45	1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha Diphosphoinositide kinase 2-alpha Phosphatidylinositol 5-phosphate 4-kinase type II alpha PtdIns(5)P-4-kinase isoform 2-alpha

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
phosphatidylinositol metabolic process	IEA	22301074

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process

Displaying 1 entry
GO Term	Evidence Code	PMID
phosphatidylinositol kinase activity	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

lipid kinase activity [inference]

phosphatidylinositol kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

phosphatidylinositol kinase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Cercopithecoidea

Group Name

Phosphatidylinositol-4-phosphate 4/5-kinase, core

Functional Category

J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
X: Mobilome: prophages, transposons

Displaying entries **11 - 15** of 15 in total

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Gene Ontology
positive regulation of autophagosome assembly
protein homodimerization activity
regulation of autophagy
transferase activity
vesicle-mediated cholesterol transport

Displaying **all 4** entries
InterPro
Phosphatidylinositol-4-phosphate 4/5-kinase, C-terminal domain superfamily
Phosphatidylinositol-4-phosphate 4/5-kinase, core
Phosphatidylinositol-4-phosphate 5-kinase, N-terminal
Phosphatidylinositol-4/5-phosphate 5/4-kinase

KEGG BRITE Database

Orthology

K00920

Name

1-phosphatidylinositol-5-phosphate 4-kinase [EC:2.7.1.149]

References

7852364

Rhea

RHEA:12280

ATP + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate)

H⁺ + ADP + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate)

Enzyme

2.7.1.149

PMID

9367159

Ortholog

Displaying entries **41 - 50** of 71 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Colobus angolensis palliatus	105527515	336983_0:00405b
Mandrillus leucophaeus	105547666	9568_0:002d90	MANLE20630
Cercocebus atys	105583793	9531_0:004986	CERAT18476
Aotus nancymaae	105715744		AOTNA22576
Propithecus coquereli	105810437		PROCO17222
Dipodomys ordii	105984505		DIPOR05689
Salmo salar	106578380		SALSA61701
Sinocyclocheilus grahami	107549201		SINGR69280
Sinocyclocheilus grahami	107595124		SINGR51096
Rhinopithecus bieti	108526629	61621_0:00091f	RHIBE10208

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OrthoDB (Group)

KEGG BRITE Database

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Acknowledgements