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7-dehydrocholesterol reductase

Summary

Gene Symbol

DHCR7

Organism

Chlorocebus sabaeus (green monkey)

External Links

NCBI Gene: 103243806
KEGG Gene ID: csab:103243806
PubChem: 103243806

Annotation

Keyword

Cholesterol biosynthesis
Endoplasmic reticulum
NADP
Oxidoreductase
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A0D9RAM9	Sterol Delta(7)-reductase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cholesterol biosynthetic process	IEA	30032202
brassinosteroid biosynthetic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

hormone metabolic process [inference]

brassinosteroid metabolic process [inference]

brassinosteroid biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid metabolic process [inference]

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

brassinosteroid metabolic process [inference]

brassinosteroid biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

secondary alcohol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid metabolic process [inference]

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

brassinosteroid metabolic process [inference]

brassinosteroid biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid metabolic process [inference]

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

brassinosteroid metabolic process [inference]

brassinosteroid biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

secondary alcohol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid metabolic process [inference]

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

brassinosteroid metabolic process [inference]

brassinosteroid biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

brassinosteroid metabolic process [inference]

brassinosteroid biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
7-dehydrocholesterol reductase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on the CH-CH group of donors [inference]

oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [inference]

7-dehydrocholesterol reductase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Cercopithecoidea

Group Name

7-dehydrocholesterol reductase

Functional Category

D: Cell cycle control, cell division, chromosome partitioning
G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying entries **1 - 10** of 12 in total

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Gene Ontology
7-dehydrocholesterol reductase activity
brassinosteroid biosynthetic process
cholesterol biosynthetic process
cholesterol metabolic process
lipid metabolic process
organic hydroxy compound biosynthetic process
oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
oxidoreductase activity, acting on the CH-CH group of donors
oxidoreductase activity
steroid biosynthetic process

Displaying **all 2** entries
InterPro
Sterol biosynthesis ERG24/DHCR-like
Sterol reductase, conserved site

KEGG BRITE Database

Orthology

K00213

Name

7-dehydrocholesterol reductase [EC:1.3.1.21]

References

9465114

Rhea

cholesterol + NADP⁺

H⁺ + 7-dehydrocholesterol + NADPH

Enzyme

1.3.1.21

PMID

Ortholog

Displaying entries **41 - 50** of 87 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Callorhinchus milii	103175009			CALMI06801
Carlito syrichta	103276625			CARSF25114
Ursus maritimus	103671131			URSMA26370
Serinus canaria	103822109			SERCA16577
Rhinopithecus roxellana	104677122	61622_0:003e9f		RHIRO07620
Macaca nemestrina	105469742	9545_0:0035a3		MACNE29252
Colobus angolensis palliatus	105503255	336983_0:00490f
Mandrillus leucophaeus	105545304	9568_0:0027d1		MANLE26358
Cercocebus atys	105577293	9531_0:0038eb		CERAT20419
Aotus nancymaae	105717672			AOTNA30073

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Last updated: December 9, 2024