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transmembrane 7 superfamily member 2

Summary

Gene Symbol

TM7SF2

Organism

Carlito syrichta (Philippine tarsier)

External Links

NCBI Gene: 103260395
KEGG Gene ID: csyr:103260395
PubChem: 103260395

Annotation

Keyword

Cholesterol biosynthesis
Endoplasmic reticulum
Oxidoreductase
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A1U7TIK2	3-beta-hydroxysterol Delta (14)-reductase C-14 sterol reductase Sterol C14-reductase Transmembrane 7 superfamily member 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
sterol biosynthetic process	IEA	22301074 30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

sterol metabolic process [inference]

sterol biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

sterol metabolic process [inference]

sterol biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

sterol metabolic process [inference]

sterol biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process

organic hydroxy compound metabolic process [inference]

sterol metabolic process [inference]

sterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
nuclear inner membrane	IEA	30032202
endoplasmic reticulum membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle inner membrane [inference]

nuclear inner membrane

nuclear membrane [inference]

nuclear inner membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on the CH-CH group of donors [inference]

oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00222

Name

Delta14-sterol reductase [EC:1.3.1.70]

References

Rhea

4,4-dimethyl-5α-cholesta-8,24-dien-3β-ol + NADP⁺

H⁺ + 4,4-dimethyl-5α-cholesta-8,14,24-trien-3β-ol + NADPH

Enzyme

1.3.1.70

PMID

Ortholog

Displaying entries **31 - 40** of 66 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Loxodonta africana	100663931		LOXAF04895
Equus caballus	100056588		HORSE05290
Sus scrofa	100514510		PIGXX16834
Bos taurus	282384		BOVIN23436
Capra hircus	100861120		CAPHI19499
Ovis aries	100037702		SHEEP11164
Dipodomys ordii	105989197		DIPOR16776
Mus musculus	73166		MOUSE26994
Rattus norvegicus	293688		RATNO19312
Cavia porcellus	100725462		CAVPO15625

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024