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ORMDL sphingolipid biosynthesis regulator 2

Summary

Gene Symbol

ORMDL2

Organism

Equus przewalskii (Przewalski's horse)

External Links

NCBI Gene: 103560203
KEGG Gene ID: epz:103560203
PubChem: 103560203

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
ceramide metabolic process	IEA	30032202
negative regulation of ceramide biosynthetic process	IEA	30032202
intracellular sphingolipid homeostasis	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

ceramide metabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular sphingolipid homeostasis

chemical homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular sphingolipid homeostasis

lipid homeostasis [inference]

intracellular sphingolipid homeostasis

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of lipid biosynthetic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of lipid metabolic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of membrane lipid metabolic process [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of nitrogen compound metabolic process [inference]

regulation of amide metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

negative regulation of lipid metabolic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of lipid biosynthetic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of membrane lipid metabolic process [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of lipid metabolic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of membrane lipid metabolic process [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of cellular component biogenesis [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA	22301074 30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Laurasiatheria

Group Name

ORM1-like protein 2

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
cellular lipid metabolic process
ceramide metabolic process
intracellular sphingolipid homeostasis
regulation of ceramide biosynthetic process
sphingolipid biosynthetic process

Displaying 1 entry
InterPro
ORMDL family

Ortholog

Displaying entries **21 - 30** of 50 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Eptesicus fuscus	103292398	29078_0:001855
Ursus maritimus	103682412	29073_0:00249e
Camelus dromedarius	105086395	9838_0:0023f4
Pteropus vampyrus	105302609	132908_0:0032f5
Equus asinus	106841308	9793_0:00448f
Rousettus aegyptiacus	107521245	9407_0:0024a6
Miniopterus natalensis	107538218	291302_0:002fb8
Hipposideros armiger	109396873	186990_0:003487
Enhydra lutris kenyoni	111160170	391180_0:003f13
Desmodus rotundus	112319095	9430_0:00121f

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Last updated: December 9, 2024