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7-dehydrocholesterol reductase

Summary

Gene Symbol

DHCR7

Organism

Corvus brachyrhynchos (American crow)

External Links

NCBI Gene: 103614711
KEGG Gene ID: cbrc:103614711
PubChem: 103614711

Annotation

Keyword

Cholesterol biosynthesis
Endoplasmic reticulum
NADP
Oxidoreductase
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A091EPT1	Sterol Delta(7)-reductase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cholesterol biosynthetic process	IEA	30032202
brassinosteroid biosynthetic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

hormone metabolic process [inference]

brassinosteroid metabolic process [inference]

brassinosteroid biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid metabolic process [inference]

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

brassinosteroid metabolic process [inference]

brassinosteroid biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

secondary alcohol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid metabolic process [inference]

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

brassinosteroid metabolic process [inference]

brassinosteroid biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid metabolic process [inference]

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

brassinosteroid metabolic process [inference]

brassinosteroid biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

secondary alcohol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid metabolic process [inference]

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

brassinosteroid metabolic process [inference]

brassinosteroid biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

phytosteroid biosynthetic process [inference]

brassinosteroid biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

brassinosteroid metabolic process [inference]

brassinosteroid biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
7-dehydrocholesterol reductase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on the CH-CH group of donors [inference]

oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [inference]

7-dehydrocholesterol reductase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Passeriformes

Group Name

7-dehydrocholesterol reductase

Functional Category

H: Coenzyme transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying entries **11 - 12** of 12 in total

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Gene Ontology
steroid metabolic process
sterol biosynthetic process

Displaying **all 2** entries
InterPro
Sterol biosynthesis ERG24/DHCR-like
Sterol reductase, conserved site

KEGG BRITE Database

Orthology

K00213

Name

7-dehydrocholesterol reductase [EC:1.3.1.21]

References

9465114

Rhea

cholesterol + NADP⁺

H⁺ + 7-dehydrocholesterol + NADPH

Enzyme

1.3.1.21

PMID

Ortholog

Displaying entries **31 - 40** of 42 in total

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Last »
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Manacus candei	127466457	415023_0:00074b
Vidua chalybeata	128790159	81927_0:0017f3
Vidua macroura	128809392	187451_0:00154b
Melozone crissalis	128936586	40204_0:00166b
Agelaius phoeniceus	129121530	39638_0:001531
Oenanthe melanoleuca	130253895	2939378_0:001995
Malurus melanocephalus	130585863	175006_0:003482
Melospiza georgiana	131084551	44398_0:001741
Ammospiza caudacuta	131559057	2857398_0:0016be
Poecile atricapillus	131585127	48891_0:0005b2

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024