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Standards Ontologies Notations
ST6 beta-galactoside alpha-2,6-sialyltransferase 1

Summary
Gene Symbol
  • ST6GAL1
Organism
Ursus maritimus (polar bear)
NCBI Gene
103676045
KEGG Gene ID
umr:103676045
PubChem
103676045
Annotation
Keyword
  • Glycoprotein
  • Golgi apparatus
  • Reference proteome
  • Signal-anchor
  • Transferase
  • Transmembrane helix
Proteins
Displaying all 2 entries
UniProt Protein Name
A0A384D9D9
A0A384D8M5
Annotation information from UniProt.
Gene Ontology (GO)
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
Sialyltransferase
Functional Category
  • H: Coenzyme transport and metabolism
  • M: Cell wall/membrane/envelope biogenesis
  • T: Signal transduction mechanisms
Displaying all 2 entries
Gene Ontology
sialyltransferase activity
transferase activity
Displaying all 2 entries
InterPro
GT29-like superfamiliy
Glycosyl transferase family 29
KEGG BRITE Database
Orthology
K00778
Name
beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 1) [EC:2.4.3.1]
References
Reactions
Displaying 1 entry
KEGG Reaction Enzyme Acceptor Product
R05990
Rhea

RHEA:21552

a β-D-Gal-(1→4)-β-D-Glc-(1↔1)-Cer(d18:1(4E)) + CMP-N-acetyl-β-neuraminate
H+ + N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide + CMP
Enzyme
PMID

RHEA:11836

N-acetyl-β-lactosamine + CMP-N-acetyl-β-neuraminate
H+ + N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosamine + CMP
Enzyme
PMID

RHEA:52104

a β-D-galactoside + CMP-N-acetyl-β-neuraminate
an N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl derivative + H+ + CMP
Enzyme
PMID
Ortholog
Displaying entries 91 - 100 of 118 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
116628086 9720_1:004a2e
116633965 9720_1:000fd0
116835529 CHEAB12116
116878269 76717_0:002a33
117034495 RHIFE06312
117999602 9715_0:00009e
118006926 9715_0:000644
118519298 9711_0:002ea7
118894403 BALMU18058
120233104 95912_0:001589
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024