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angiotensin-converting enzyme

Summary

Gene Symbol

LOC103744762

Organism

Nannospalax galili (Upper Galilee mountains blind mole rat)

External Links

NCBI Gene: 103744762
PubChem: 103744762

Annotation

Keyword

Carboxypeptidase
Disulfide bond
Glycoprotein
Metal-binding
Metalloprotease
Reference proteome
Repeat
Signal
Transmembrane helix
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A8C6R1B2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
proteolysis	IEA	22301074 30032202
positive regulation of systemic arterial blood pressure
regulation of systemic arterial blood pressure by renin-angiotensin

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

multicellular organismal process [inference]

system process [inference]

endocrine process [inference]

regulation of systemic arterial blood pressure by hormone [inference]

regulation of systemic arterial blood pressure by renin-angiotensin

biological regulation [inference]

regulation of biological quality [inference]

regulation of blood pressure [inference]

regulation of systemic arterial blood pressure [inference]

regulation of systemic arterial blood pressure mediated by a chemical signal [inference]

regulation of systemic arterial blood pressure by hormone [inference]

regulation of systemic arterial blood pressure by renin-angiotensin

positive regulation of blood pressure [inference]

positive regulation of systemic arterial blood pressure

Displaying **all 3** entries
GO Term	Evidence Code	PMID
plasma membrane	IEA	30032202
extracellular region
cytoplasm

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
peptidyl-dipeptidase activity	IEA	22301074 30032202
metal ion binding
metallopeptidase activity	IEA	22301074 30032202
carboxypeptidase activity

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

metallopeptidase activity

exopeptidase activity [inference]

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

metallopeptidase activity

exopeptidase activity [inference]

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

angiotensin-converting enzyme

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 8** entries
Gene Ontology
carboxypeptidase activity
hydrolase activity
metal ion binding
metallopeptidase activity
peptidyl-dipeptidase activity
positive regulation of systemic arterial blood pressure
proteolysis
regulation of systemic arterial blood pressure by renin-angiotensin

Displaying 1 entry
InterPro
Peptidase M2, peptidyl-dipeptidase A

Ortholog

Displaying entries **31 - 40** of 58 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Mus caroli	110304805	10089_0:003591
Mus pahari	110331687	10093_0:003402
Urocitellus parryii	113192186	9999_0:002a6f
Bos indicus x Bos taurus	113877790		BOBOX13837
Marmota flaviventris	114101309	93162_0:003247
Grammomys surdaster	114632022	491861_0:002b1b
Peromyscus leucopus	114690399	10041_0:00520b
Mastomys coucha	116077933	35658_0:004364
Rattus rattus	116909348	10117_0:003726
Arvicanthis niloticus	117711678	61156_0:002027