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leukotriene A4 hydrolase

Summary

Gene Symbol

LTA4H

Organism

Serinus canaria (Common canary)

External Links

NCBI Gene: 103813389
KEGG Gene ID: scan:103813389
PubChem: 103813389

Annotation

Keyword

Cytoplasm
Leukotriene biosynthesis
Metal-binding
Metalloprotease
Reference proteome
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A8C9MWL7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
leukotriene biosynthetic process	IEA	30032202
peptide catabolic process	IEA	30032202
proteolysis	IEA	22301074

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

peptide metabolic process [inference]

peptide catabolic process

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide catabolic process

protein metabolic process [inference]

proteolysis

organonitrogen compound catabolic process [inference]

peptide catabolic process

catabolic process [inference]

cellular catabolic process [inference]

peptide catabolic process

organic substance catabolic process [inference]

organonitrogen compound catabolic process [inference]

peptide catabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

leukotriene metabolic process [inference]

leukotriene biosynthetic process

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

cellular catabolic process [inference]

peptide catabolic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

leukotriene metabolic process [inference]

leukotriene biosynthetic process

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

leukotriene metabolic process [inference]

leukotriene biosynthetic process

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide catabolic process

protein metabolic process [inference]

proteolysis

organonitrogen compound catabolic process [inference]

peptide catabolic process

organic substance catabolic process [inference]

organonitrogen compound catabolic process [inference]

peptide catabolic process

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

leukotriene metabolic process [inference]

leukotriene biosynthetic process

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

cellular catabolic process [inference]

peptide catabolic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
nucleus	IEA	30032202
cytosol	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 5** entries
GO Term	Evidence Code	PMID
zinc ion binding	IEA	22301074
metallopeptidase activity	IEA	22301074
aminopeptidase activity	IEA	30032202
leukotriene-A4 hydrolase activity	IEA	30032202
epoxide hydrolase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

metallopeptidase activity

exopeptidase activity [inference]

aminopeptidase activity

hydrolase activity, acting on ether bonds [inference]

ether hydrolase activity [inference]

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

metallopeptidase activity

exopeptidase activity [inference]

aminopeptidase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K01254

Name

leukotriene-A4 hydrolase [EC:3.3.2.6]

References

Rhea

H₂O + leukotriene A₄

leukotriene B₄

Enzyme

3.3.2.6

PMID

Ortholog

Displaying entries **51 - 60** of 81 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Heterocephalus glaber	101700383		HETGA03244
Anolis carolinensis	100565831		ANOCA07033
Vombatus ursinus	114038545		VOMUR22791
Bos indicus x Bos taurus	113892781		BOBOX39402
Vicugna pacos	102534137		VICPA03735
Otolemur garnettii	100963995		OTOGA17546
Chinchilla lanigera	102007852		CHILA01207
Aotus nancymaae	105728751		AOTNA02023
Phascolarctos cinereus	110221755		PHACI17116
Saimiri boliviensis boliviensis	101048856		SAIBB16068

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Last updated: August 19, 2024