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myosin light chain 9

Summary

Gene Symbol

MYL9

Organism

Homo sapiens (human)

External Links

NCBI Gene

10398

PubChem

10398

Alliance of Genome Resources

HGNC:15754

Annotation

Keyword

Acetylation
Alternative splicing
Calcium
Cytoskeleton
Metal-binding
Muscle protein
Myosin
Phosphoprotein
Reference proteome
Repeat

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A384NY64	Myosin regulatory light chain 2, smooth muscle isoform Myosin regulatory light chain 9
P24844	20 kDa myosin light chain MLC-2C Myosin RLC Myosin regulatory light chain 2, smooth muscle isoform Myosin regulatory light chain 9 Myosin regulatory light chain MRLC1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
regulation of muscle contraction	TAS	2526655
myofibril assembly	IBA
stress fiber assembly	IDA	39106863
platelet aggregation	HMP	23382103

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

homotypic cell-cell adhesion [inference]

platelet aggregation

actin filament-based process [inference]

actin cytoskeleton organization [inference]

actomyosin structure organization [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization [inference]

actomyosin structure organization [inference]

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

myofibril assembly

cellular component assembly [inference]

cellular component assembly involved in morphogenesis [inference]

myofibril assembly

actin filament bundle assembly [inference]

contractile actin filament bundle assembly [inference]

stress fiber assembly

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

myofibril assembly

supramolecular fiber organization [inference]

actin filament organization [inference]

actin filament bundle organization [inference]

actin filament bundle assembly [inference]

contractile actin filament bundle assembly [inference]

stress fiber assembly

myofibril assembly

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

cellular component assembly involved in morphogenesis [inference]

myofibril assembly

biological regulation [inference]

regulation of biological process [inference]

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of muscle system process [inference]

regulation of muscle contraction

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
stress fiber	IDA	39106863
stress fiber	IBA
cytoplasm	IBA
cytosol	TAS
muscle myosin complex	TAS	2526655

GO Hierarchy

cellular component

protein-containing complex [inference]

myosin complex [inference]

myosin II complex

muscle myosin complex

cellular anatomical entity [inference]

cytoplasm

cell cortex

actin filament bundle [inference]

contractile actin filament bundle [inference]

stress fiber

actomyosin [inference]

stress fiber

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

contractile fiber [inference]

myofibril

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

contractile fiber [inference]

myofibril

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

contractile fiber [inference]

myofibril

Displaying **all 5** entries
GO Term	Evidence Code	PMID
structural constituent of cytoskeleton	IDA	39106863
calcium ion binding	IEA
protein binding	IPI	32296183
structural constituent of muscle	TAS	2526655
myosin heavy chain binding	IBA

GO Hierarchy

molecular function

structural molecule activity [inference]

binding [inference]

protein binding

cytoskeletal protein binding [inference]

myosin binding [inference]

myosin heavy chain binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

myosin light chain, regulatory A

Functional Category

I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
calcium ion binding
metal ion binding

Displaying **all 3** entries
InterPro
EF-Hand 1, calcium-binding site
EF-hand domain pair
EF-hand domain

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0060610	megacystis-microcolon-intestinal hypoperistalsis syndrome	Alliance of Genome Resources
DOID:0080326	familial hypertrophic cardiomyopathy	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of 98 in total

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Species	Gene ID	Orthologous MAtrix
Nomascus leucogenys	100593242	NOMLE07549
Loxodonta africana	100672436	LOXAF13119
Oreochromis niloticus	100697131	ORENI58862
Cavia porcellus	100725728	CAVPO16422
Cricetulus griseus	100753477	CRIGR02899
Sarcophilus harrisii	100917897	SARHA18305
Otolemur garnettii	100940607	OTOGA13539
Pan paniscus	100995742	PANPA22226
Papio anubis	101002500	PAPAN12584
Saimiri boliviensis boliviensis	101037608	SAIBB19966

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OrthoDB (Group)

International Collaboration

Acknowledgements