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integrin alpha 9

Summary

Gene Symbol

Itga9

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

104099

PubChem

104099

Alliance of Genome Resources

MGI:104756

Annotation

Keyword

Calcium
Cell adhesion
Disulfide bond
Glycoprotein
Integrin
Metal-binding
Proteomics identification
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
B8JK39
Q3UT74
E9QAP0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
cell-matrix adhesion	IBA IEA
cell-cell adhesion	IBA
cell adhesion mediated by integrin	IBA
neutrophil chemotaxis	IGI	21321126
cell adhesion	ISO

GO Hierarchy

biological process

immune system process [inference]

leukocyte migration [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

myeloid leukocyte migration [inference]

granulocyte migration [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

neutrophil migration [inference]

neutrophil chemotaxis

cellular process [inference]

cell-substrate adhesion [inference]

cell-matrix adhesion

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

myeloid leukocyte migration [inference]

granulocyte migration [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

neutrophil migration [inference]

neutrophil chemotaxis

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction [inference]

negative regulation of vasoconstriction

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of vasoconstriction

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of vasoconstriction [inference]

negative regulation of vasoconstriction

negative regulation of multicellular organismal process [inference]

negative regulation of vasoconstriction

regulation of biological quality [inference]

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction [inference]

negative regulation of vasoconstriction

Displaying **all 5** entries
GO Term	Evidence Code	PMID
external side of plasma membrane	IBA
membrane
integrin alpha9-beta1 complex	IDA ISO	22654117
integrin complex	IBA
basal plasma membrane	IDA	7534781

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

integrin alpha9-beta1 complex

protein complex involved in cell adhesion [inference]

integrin complex

integrin alpha9-beta1 complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

integrin alpha9-beta1 complex

cellular anatomical entity [inference]

plasma membrane region [inference]

basal plasma membrane

side of membrane [inference]

external side of plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
integrin binding	IBA
integrin binding involved in cell-matrix adhesion	IDA	22654117
metal ion binding	IEA
collagen binding	IEA ISO
laminin binding	IEA ISO

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

integrin binding

integrin binding involved in cell-matrix adhesion

laminin binding

cell adhesion molecule binding [inference]

integrin binding

integrin binding involved in cell-matrix adhesion

cell adhesion mediator activity [inference]

cell-matrix adhesion mediator activity [inference]

integrin binding involved in cell-matrix adhesion

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

integrin binding

integrin binding involved in cell-matrix adhesion

collagen binding

extracellular matrix binding [inference]

laminin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

integrin alpha-9

Functional Category

D: Cell cycle control, cell division, chromosome partitioning
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
cell adhesion mediated by integrin
cell-matrix adhesion
integrin binding
integrin-mediated signaling pathway

Disease

Disease Ontology

Displaying **all 5** entries
DO ID	Disease Name	Source
DOID:0060646	congenital chylothorax	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources
DOID:1793	pancreatic cancer	Alliance of Genome Resources
DOID:3526	cerebral infarction	Alliance of Genome Resources
DOID:3908	lung non-small cell carcinoma	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **108** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	3680		HGNC:6145	HUMAN69180
Drosophila melanogaster	36692		FB:FBgn0286785
Drosophila melanogaster	36693		FB:FBgn0034005
Drosophila melanogaster	37732		FB:FBgn0034880
Danio rerio	394012		ZFIN:ZDB-GENE-040426-1129	DANRE06476
Pan troglodytes	470789			PANTR30760
Canis lupus familiaris	477021			CANLF08944
Bos taurus	532127			BOVIN17242
Canis lupus familiaris	608986			CANLF08944
Rattus norvegicus	685004	10116_1:002c5f	RGD:1311191	RATNO41992

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Last updated: December 9, 2024