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MIRAGE
glycine decarboxylase

Summary
Gene Symbol
  • Gldc
Organism
Mus musculus (house mouse)
NCBI Gene
104174
PubChem
104174
Alliance of Genome Resources
Annotation
Keyword
  • Acetylation
  • Direct protein sequencing
  • Mitochondrion
  • Oxidoreductase
  • Pyridoxal phosphate
  • Reference proteome
  • Transit peptide
Proteins
Displaying 1 entry
UniProt Protein Name
Q91W43
  • Glycine cleavage system P protein
  • Glycine decarboxylase
  • Glycine dehydrogenase (aminomethyl-transferring)
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 9 in total
GO Term Evidence Code PMID
glycine catabolic process
glycine catabolic process
glycine decarboxylation via glycine cleavage system
glycine decarboxylation via glycine cleavage system
response to methylamine
GO Hierarchy
Displaying entries 1 - 5 of 15 in total
GO Term Evidence Code PMID
glycine dehydrogenase (decarboxylating) activity
glycine dehydrogenase (decarboxylating) activity
glycine dehydrogenase (decarboxylating) activity
glycine binding
glycine binding
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
glycine dehydrogenase
Functional Category
  • E: Amino acid transport and metabolism
  • I: Lipid transport and metabolism
  • Q: Secondary metabolites biosynthesis, transport and catabolism
Displaying all 8 entries
Gene Ontology
catalytic activity
glycine binding
glycine catabolic process
glycine decarboxylation via glycine cleavage system
glycine dehydrogenase (decarboxylating) activity
glycine metabolic process
oxidoreductase activity
pyridoxal phosphate binding
Displaying all 7 entries
InterPro
Glycine cleavage system P protein
Glycine cleavage system P-protein, N-terminal domain
Glycine dehydrogenase (decarboxylating)
Glycine dehydrogenase, C-terminal domain
Pyridoxal phosphate-dependent transferase, major domain
Pyridoxal phosphate-dependent transferase, small domain
Pyridoxal phosphate-dependent transferase
Disease
Disease Ontology
Displaying 1 entry
DO ID Disease Name Source
DOID:9268 glycine encephalopathy
Ortholog
Displaying entries 1 - 10 of 83 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
2731 Xenbase:XB-GENE-1221322 HUMAN96407
104174 Xenbase:XB-GENE-1221322
309312 RATNO18265
464987 PANTR43625
481534 CANLF02169
507688 BOVIN34341
715563 MACMU12829
100018555 MONDO29566
100060355 HORSE21867
100076326 ORNAN32204
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025