GlyCosmos Portal

GlyTouCan

Glycan Structure Repository

GlyComb

Glycoconjugate Repository

GlycoPOST

Glycomics MS raw data Repository

UniCarb-DR

Glycomics MS Repository for glycan annotations from GlycoWorkbench

LM-GlycoRepo

Repository for lectin-assisted multimodality data

All Resources

Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms

Other Information

Release Statistics Download

Tools

Glycan Converters

LM-GlycomeAtlas

Search Tools

Cross Search Glycan Search Publication Search Programmatic Access

Guidelines

MIRAGE

3-hydroxyacyl-CoA dehydratase 3

Summary

Gene Symbol

HACD3

Organism

Rhinopithecus roxellana (golden snub-nosed monkey)

External Links

NCBI Gene: 104655951
KEGG Gene ID: rro:104655951
PubChem: 104655951

Annotation

Keyword

Coiled coil
Endoplasmic reticulum
Fatty acid biosynthesis
Lyase
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A2K6NQ62

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
sphingolipid biosynthetic process	IEA	30032202
fatty acid elongation	IEA	30032202
very long-chain fatty acid biosynthetic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
3-hydroxyacyl-CoA dehydratase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

lyase activity [inference]

carbon-oxygen lyase activity [inference]

hydro-lyase activity [inference]

enoyl-CoA hydratase activity [inference]

3-hydroxyacyl-CoA dehydratase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 8** entries
Gene Ontology
3-hydroxyacyl-CoA dehydratase activity
fatty acid elongation
fatty acid metabolic process
lipid metabolic process
lyase activity
sphingolipid biosynthetic process
very long-chain fatty acid biosynthetic process
very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity

Displaying 1 entry
InterPro
Protein-tyrosine phosphatase-like, PTPLA

KEGG BRITE Database

Orthology

K10703

Name

very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]

References

Rhea

a very-long-chain (3R)-3-hydroxyacyl-CoA

H₂O + a very-long-chain (2E)-enoyl-CoA

Enzyme

4.2.1.134

PMID

Ortholog

Displaying entries **11 - 20** of 88 in total

« First

‹ Prev

1

2

3

4

5

6

…

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Pongo abelii	100174644		PONAB08810
Ciona intestinalis	100175762		CIOIN06857
Oryctolagus cuniculus	100339262		RABIT05969
Callithrix jacchus	100413343		CALJA01001
Ailuropoda melanoleuca	100476116		AILME17823
Meleagris gallopavo	100542802		MELGA03242
Anolis carolinensis	100555369		ANOCA13160
Nomascus leucogenys	100604226		NOMLE32341
Loxodonta africana	100666774		LOXAF05998
Oreochromis niloticus	100702753		ORENI33733

About Release Notes Help Feedback

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: support@glycosmos.org

GlyCosmos Portal v4.4.0

Last updated: December 8, 2025