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translocase of inner mitochondrial membrane 44

Summary

Gene Symbol

TIMM44

Organism

Homo sapiens (human)

External Links

NCBI Gene

10469

PubChem

10469

Alliance of Genome Resources

HGNC:17316

JoGo

TIMM44

TogoVar

TIMM44

Annotation

Keyword

3D-structure
ATP-binding
Mitochondrion inner membrane
Phosphoprotein
Proteomics identification
Reference proteome
Transit peptide
Translocation

Proteins

Displaying 1 entry
UniProt	Protein Name
O43615

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein targeting to mitochondrion	TAS	10339406
intracellular protein transport	NAS	10339406
protein import into mitochondrial matrix	IBA

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to organelle [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

establishment of protein localization to mitochondrion [inference]

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to mitochondrion

protein transport [inference]

intracellular protein transport

protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

establishment of protein localization to organelle [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

establishment of protein localization to mitochondrion [inference]

transmembrane transport [inference]

protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

mitochondrial transmembrane transport [inference]

protein import into mitochondrial matrix

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to organelle [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

establishment of protein localization to mitochondrion [inference]

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to mitochondrion

protein transport [inference]

intracellular protein transport

protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

establishment of protein localization to organelle [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

establishment of protein localization to mitochondrion [inference]

establishment of localization [inference]

transport [inference]

mitochondrial transport [inference]

mitochondrial transmembrane transport [inference]

protein import into mitochondrial matrix

intracellular transport [inference]

intracellular protein transport

transmembrane transport [inference]

protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

mitochondrial transmembrane transport [inference]

protein import into mitochondrial matrix

organic substance transport [inference]

protein transport [inference]

intracellular protein transport

protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport

protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to mitochondrion

protein transport [inference]

intracellular protein transport

protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

establishment of protein localization to organelle [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

establishment of protein localization to mitochondrion [inference]

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to organelle [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

establishment of protein localization to mitochondrion [inference]

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to mitochondrion

protein transport [inference]

intracellular protein transport

protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

establishment of protein localization to organelle [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

establishment of protein localization to mitochondrion [inference]

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
fibrillar center	IDA
mitochondrion	IDA
mitochondrion	HTP	34800366
mitochondrial inner membrane	NAS	10339406
mitochondrial inner membrane	IDA	10339406 20053669

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

inner mitochondrial membrane protein complex [inference]

TIM23 mitochondrial import inner membrane translocase complex

mitochondrial protein-containing complex [inference]

inner mitochondrial membrane protein complex [inference]

TIM23 mitochondrial import inner membrane translocase complex

cellular anatomical entity [inference]

fibrillar center

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

mitochondrial matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	12620389 25416956 25910212 32296183 32814053
ATP binding	IEA
protein-folding chaperone binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

protein-folding chaperone binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

subunit TIM44 of mitochondrial import inner membrane translocase

Functional Category

I: Lipid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
protein import into mitochondrial matrix
protein-folding chaperone binding

Displaying **all 4** entries
InterPro
Mitochondrial import inner membrane translocase subunit Tim44
NTF2-like domain superfamily
Tim44-like domain
Tim44-like

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements