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MIRAGE
prostaglandin-endoperoxide synthase 1

Summary
Gene Symbol
  • PTGS1
Organism
Bison bison bison
NCBI Gene
104997385
KEGG Gene ID
bbis:104997385
PubChem
104997385
Annotation
Keyword
  • Dioxygenase
  • EGF-like domain
  • Heme
  • Microsome
  • Peroxidase
  • Prostaglandin biosynthesis
  • Reference proteome
Proteins
Displaying 1 entry
UniProt Protein Name
A0A6P3I7H3
  • Cyclooxygenase-1
  • Prostaglandin H2 synthase 1
  • Prostaglandin-endoperoxide synthase 1
Annotation information from UniProt.
Gene Ontology (GO)
Displaying all 2 entries
GO Term Evidence Code PMID
cyclooxygenase pathway
response to oxidative stress
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Artiodactyla
Group Name
prostaglandin G/H synthase 1
Functional Category
  • C: Energy production and conversion
  • M: Cell wall/membrane/envelope biogenesis
  • T: Signal transduction mechanisms
Displaying entries 1 - 10 of 13 in total
Gene Ontology
cellular oxidant detoxification
cyclooxygenase pathway
dioxygenase activity
fatty acid metabolic process
heme binding
lipid metabolic process
metal ion binding
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
oxidoreductase activity
prostaglandin biosynthetic process
Displaying all 4 entries
InterPro
EGF-like domain
Haem peroxidase domain superfamily, animal type
Haem peroxidase superfamily
Haem peroxidase, animal-type
KEGG BRITE Database
Orthology
K00509
Name
prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1]
References
Rhea

RHEA:23728

O2 + AH2 + (5Z,8Z,11Z,14Z)-eicosatetraenoate
A + H2O + prostaglandin H2
Enzyme
PMID
Ortholog
Displaying entries 1 - 10 of 24 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
282022 9913_0:002378
397541 9823_0:000271
443551 9940_0:001199
101325470 9739_0:001870
102170328 9925_0:002258
102287995 72004_1:001a62
102395640 89462_0:003423
102507716 419612_0:000a20
102537567 30538_0:0008ee
102996994 9755_0:001ae2
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024