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cardiolipin synthase 1

Summary

Gene Symbol

CRLS1

Organism

Pteropus vampyrus (large flying fox)

External Links

NCBI Gene: 105298697
KEGG Gene ID: pvp:105298697
PubChem: 105298697

Annotation

Keyword

Phospholipid biosynthesis
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A6P3R579

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
cardiolipin biosynthetic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane	IEA	22301074
mitochondrion	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cardiolipin synthase activity	IEA	30032202
CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

phosphotransferase activity, for other substituted phosphate groups [inference]

CDP-alcohol phosphatidyltransferase activity [inference]

CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity

phosphatidyltransferase activity [inference]

cardiolipin synthase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K08744

Name

cardiolipin synthase (CMP-forming) [EC:2.7.8.41]

References

Rhea

a CDP-1,2-diacyl-sn-glycerol + 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)

H⁺ + CMP + a cardiolipin

Enzyme

2.7.8.41

PMID

Ortholog

Displaying entries **31 - 40** of 41 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Rhinolophus ferrumequinum	117016123		RHIFE23968
Ficedula albicollis	101806475		FICAL07147
Chlorocebus sabaeus	103246789		CHLSB07735
Rhinopithecus bieti	108533240		RHIBE03893
Nomascus leucogenys	100589978		NOMLE03011
Podarcis muralis	114593653		PODMU16846
Athene cunicularia	113477784		ATHCN05167
Propithecus coquereli	105806222		PROCO15951
Nannospalax galili	103725545		NANGA20988
Corvus moneduloides	116441506		CORMO17876

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024