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protein tyrosine phosphatase receptor type N2

Summary

Gene Symbol

PTPRN2

Organism

Macaca nemestrina (pig-tailed macaque)

External Links

NCBI Gene: 105474981
PubChem: 105474981

Annotation

Keyword

Acetylation
Cytoplasmic vesicle
Glycoprotein
Phospholipid metabolism
Phosphoprotein
Protein phosphatase
Receptor
Reference proteome
Signal
Synapse
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
O02695	M1851

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein dephosphorylation	IEA	22301074
lipid metabolic process
neurotransmitter secretion
insulin secretion involved in cellular response to glucose stimulus	IEA	30032202
regulation of secretion	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation

primary metabolic process [inference]

lipid metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

organic substance metabolic process [inference]

lipid metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein dephosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion [inference]

insulin secretion [inference]

insulin secretion involved in cellular response to glucose stimulus

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

insulin secretion [inference]

insulin secretion involved in cellular response to glucose stimulus

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

insulin secretion [inference]

insulin secretion involved in cellular response to glucose stimulus

export from cell [inference]

secretion by cell [inference]

protein secretion [inference]

insulin secretion [inference]

insulin secretion involved in cellular response to glucose stimulus

signal release [inference]

hormone secretion [inference]

peptide hormone secretion [inference]

insulin secretion [inference]

insulin secretion involved in cellular response to glucose stimulus

signal release from synapse [inference]

neurotransmitter secretion

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion [inference]

insulin secretion [inference]

insulin secretion involved in cellular response to glucose stimulus

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

insulin secretion [inference]

insulin secretion involved in cellular response to glucose stimulus

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

insulin secretion [inference]

insulin secretion involved in cellular response to glucose stimulus

establishment of localization [inference]

transport [inference]

neurotransmitter transport [inference]

neurotransmitter secretion

hormone transport [inference]

hormone secretion [inference]

peptide hormone secretion [inference]

insulin secretion [inference]

insulin secretion involved in cellular response to glucose stimulus

secretion [inference]

peptide secretion [inference]

peptide hormone secretion [inference]

insulin secretion [inference]

insulin secretion involved in cellular response to glucose stimulus

secretion by cell [inference]

protein secretion [inference]

insulin secretion [inference]

insulin secretion involved in cellular response to glucose stimulus

signal release [inference]

hormone secretion [inference]

peptide hormone secretion [inference]

insulin secretion [inference]

insulin secretion involved in cellular response to glucose stimulus

signal release from synapse [inference]

neurotransmitter secretion

organic substance transport [inference]

protein transport [inference]

protein secretion [inference]

insulin secretion [inference]

insulin secretion involved in cellular response to glucose stimulus

peptide transport [inference]

peptide secretion [inference]

peptide hormone secretion [inference]

insulin secretion [inference]

insulin secretion involved in cellular response to glucose stimulus

nitrogen compound transport [inference]

protein transport [inference]

protein secretion [inference]

insulin secretion [inference]

insulin secretion involved in cellular response to glucose stimulus

amide transport [inference]

peptide transport [inference]

peptide secretion [inference]

peptide hormone secretion [inference]

insulin secretion [inference]

insulin secretion involved in cellular response to glucose stimulus

export from cell [inference]

secretion by cell [inference]

protein secretion [inference]

insulin secretion [inference]

insulin secretion involved in cellular response to glucose stimulus

signal release [inference]

hormone secretion [inference]

peptide hormone secretion [inference]

insulin secretion [inference]

insulin secretion involved in cellular response to glucose stimulus

signal release from synapse [inference]

neurotransmitter secretion

establishment of protein localization [inference]

protein transport [inference]

protein secretion [inference]

insulin secretion [inference]

insulin secretion involved in cellular response to glucose stimulus

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

insulin secretion [inference]

insulin secretion involved in cellular response to glucose stimulus

establishment of localization in cell [inference]

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion [inference]

insulin secretion [inference]

insulin secretion involved in cellular response to glucose stimulus

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

insulin secretion [inference]

insulin secretion involved in cellular response to glucose stimulus

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

insulin secretion [inference]

insulin secretion involved in cellular response to glucose stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone transport [inference]

hormone secretion [inference]

peptide hormone secretion [inference]

insulin secretion [inference]

insulin secretion involved in cellular response to glucose stimulus

Displaying **all 4** entries
GO Term	Evidence Code	PMID
secretory granule	IEA	30032202
secretory granule membrane
synaptic vesicle membrane
synapse	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

secretory granule membrane

bounding membrane of organelle [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

secretory granule membrane

cell junction [inference]

synapse

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

Displaying 1 entry
GO Term	Evidence Code	PMID
protein tyrosine phosphatase activity	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Aminopeptidase

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
aminopeptidase activity
hydrolase activity
metal ion binding
metalloaminopeptidase activity
metallopeptidase activity
proteolysis
zinc ion binding

Displaying **all 2** entries
InterPro
Peptidase M18, domain 2
Peptidase M18

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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OrthoDB (Group)

International Collaboration

Acknowledgements