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Standards Ontologies Notations
phospholipase C beta 2

Summary
Gene Symbol
  • PLCB2
Organism
Macaca nemestrina (pig-tailed macaque)
NCBI Gene
105492354
KEGG Gene ID
mni:105492354
PubChem
105492354
Annotation
Keyword
  • Calcium
  • Coiled coil
  • Hydrolase
  • Lipid degradation
  • Metal-binding
  • Phosphoprotein
  • Reference proteome
  • Transducer
Proteins
Displaying 1 entry
UniProt Protein Name
A0A2K6B8P3
Annotation information from UniProt.
Gene Ontology (GO)
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Cercopithecoidea
Group Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
Functional Category
  • F: Nucleotide transport and metabolism
  • T: Signal transduction mechanisms
  • V: Defense mechanisms
Displaying all 7 entries
Gene Ontology
calcium ion binding
hydrolase activity
lipid metabolic process
metal ion binding
phosphatidylinositol phospholipase C activity
phosphatidylinositol-mediated signaling
release of sequestered calcium ion into cytosol
Displaying entries 1 - 10 of 14 in total
InterPro
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2, EF-hand domain
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2, catalytic domain
C2 domain superfamily
C2 domain
EF-hand domain pair
PLC-beta, PH domain
PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta
Phosphatidylinositol-specific phospholipase C, X domain
Phosphoinositide phospholipase C family
KEGG BRITE Database
Orthology
K05858
Name
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
References
Rhea

RHEA:33179

H2O + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate)
H+ + a 1,2-diacyl-sn-glycerol + 1D-myo-inositol 1,4,5-trisphosphate
Enzyme
PMID
Ortholog
Displaying entries 71 - 80 of 80 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
115544368 GADMO49430
115606933 STRHB08899
116445835 CORMO23938
116837811 CHEAB13591
117024110 RHIFE31316
117070870 54180_1:003e21
118286622 SCOMX11317
122222194 PANLE19154
123804253 URSAM21396
126959796 257877_1:001e5a
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024