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protein O-fucosyltransferase 1

Summary

Gene Symbol

POFUT1

Organism

Macaca nemestrina (pig-tailed macaque)

External Links

NCBI Gene: 105496184
KEGG Gene ID: mni:105496184
PubChem: 105496184

Annotation

Keyword

Disulfide bond
Fucose metabolism
Reference proteome
Signal
Transferase

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A2K6CJE0	Peptide-O-fucosyltransferase 1
A0A2K6CJD5	Peptide-O-fucosyltransferase 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
Notch signaling pathway	IEA	22301074 30032202
protein O-linked fucosylation	IEA	22301074 30032202
regulation of Notch signaling pathway	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

glycosylation [inference]

fucosylation [inference]

protein O-linked fucosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying 1 entry
GO Term	Evidence Code	PMID
peptide-O-fucosyltransferase activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

fucosyltransferase activity [inference]

peptide-O-fucosyltransferase activity

catalytic activity, acting on a protein [inference]

peptide-O-fucosyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K03691

Name

peptide-O-fucosyltransferase [EC:2.4.1.221]

References

11524432

Rhea

GDP-β-L-fucose

H⁺ + GDP

Enzyme

2.4.1.221

PMID

GDP-β-L-fucose

H⁺ + GDP

Enzyme

2.4.1.221

PMID

GDP-β-L-fucose

H⁺ + GDP

Enzyme

2.4.1.221

PMID

GDP-β-L-fucose

H⁺ + GDP

Enzyme

2.4.1.221

PMID

Ortholog

Displaying entries **41 - 50** of 77 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Cricetulus griseus	100753417		CRIGR09875
Mus musculus	140484		MOUSE31766
Rattus norvegicus	311551		RATNO28480
Octodon degus	101580725		OCTDE08560
Heterocephalus glaber	101707778		HETGA20795
Monodelphis domestica	100010283		MONDO01670
Pelodiscus sinensis	102443515		PELSI03886
Anolis carolinensis	100557912		ANOCA13232
Vombatus ursinus	114047329		VOMUR05324
Bos indicus x Bos taurus	113903137		BOBOX02383

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024