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solute carrier family 39 member 8

Summary

Gene Symbol

SLC39A8

Organism

Mandrillus leucophaeus (drill)

External Links

NCBI Gene: 105548313
KEGG Gene ID: mleu:105548313
PubChem: 105548313

Annotation

Keyword

Reference proteome
Signal
Transmembrane helix
Zinc transport

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A2K5XP35
A0A2K5XP66

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
intracellular zinc ion homeostasis	IEA	30032202
zinc ion import across plasma membrane	IEA	30032202

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

zinc ion transmembrane transport [inference]

zinc ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

zinc ion transmembrane transport [inference]

zinc ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

zinc ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

zinc ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

zinc ion import across plasma membrane

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular zinc ion homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular zinc ion homeostasis

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular zinc ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular zinc ion homeostasis

inorganic ion homeostasis [inference]

intracellular zinc ion homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

transition metal ion transport [inference]

zinc ion transport [inference]

zinc ion transmembrane transport [inference]

zinc ion import across plasma membrane

monoatomic cation transmembrane transport [inference]

zinc ion transmembrane transport [inference]

zinc ion import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

zinc ion transmembrane transport [inference]

zinc ion import across plasma membrane

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

zinc ion transmembrane transport [inference]

zinc ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

zinc ion transmembrane transport [inference]

zinc ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

zinc ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

zinc ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

zinc ion import across plasma membrane

import into cell [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

zinc ion import across plasma membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
membrane	IEA	22301074

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
zinc ion transmembrane transporter activity	IEA	30032202

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

transition metal ion transmembrane transporter activity [inference]

zinc ion transmembrane transporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

transition metal ion transmembrane transporter activity [inference]

zinc ion transmembrane transporter activity

salt transmembrane transporter activity [inference]

zinc ion transmembrane transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Cercopithecoidea

Group Name

metal cation symporter ZIP8

Functional Category

I: Lipid transport and metabolism
P: Inorganic ion transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying entries **11 - 16** of 16 in total

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Gene Ontology
negative regulation of canonical NF-kappaB signal transduction
plasma membrane selenite transport
regulation of membrane potential
zinc ion transmembrane transport
zinc ion transmembrane transporter activity
zinc ion transport

Displaying 1 entry
InterPro
Zinc/iron permease

KEGG BRITE Database

Orthology

K14714

Name

solute carrier family 39 (zinc transporter), member 8

References

12504855

Ortholog

Displaying entries **51 - 60** of 74 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Cyprinodon variegatus	107096797			CYPVA22083
Sinocyclocheilus grahami	107587097			SINGR41282
Ictalurus punctatus	108263549			ICTPU27143
Ictalurus punctatus	108277197			ICTPU25300
Pygocentrus nattereri	108432418			PYGNA15686
Rhinopithecus bieti	108532819	61621_0:001741		RHIBE18044
Cyprinus carpio carpio	109055878			CYPCA85936
Piliocolobus tephrosceles	111547970	591936_0:000ec6
Amphiprion ocellaris	111578757			AMPOC19715
Theropithecus gelada	112624978	9565_0:00168d

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024