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solute carrier family 35 member A1

Summary

Gene Symbol

SLC35A1

Aliases

CMP-Sia-Tr
CMP-sialic acid transporter
CMPST
hCST

Organism

Homo sapiens (human)

External Links

NCBI Gene

10559

GGDB ID

gg178

HGNC

11021

mRNA

NM_006416

map

6q15

Protein

NP_006407

OMIM

605634

KEGG Gene ID

hsa:10559

PubChem

10559

Alliance of Genome Resources

HGNC:11021

JoGo

SLC35A1

TogoVar

SLC35A1

Annotation

Keyword

Alternative splicing
Antiport
Congenital disorder of glycosylation
Disease variant
Golgi apparatus
Proteomics identification
Reference proteome
Sugar transport
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P78382	Solute carrier family 35 member A1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
carbohydrate metabolic process	TAS	9644260
N-acetylneuraminate metabolic process	IEA
CMP-N-acetylneuraminate biosynthetic process	IEA
CMP-N-acetylneuraminate transmembrane transport	ISS
CMP-N-acetylneuraminate transmembrane transport	IDA	15576474

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

CMP-N-acetylneuraminate metabolic process [inference]

CMP-N-acetylneuraminate biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

amide metabolic process [inference]

N-acetylneuraminate metabolic process

organonitrogen compound metabolic process [inference]

N-acetylneuraminate metabolic process

protein metabolic process [inference]

protein modification process

biosynthetic process [inference]

cellular biosynthetic process [inference]

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

CMP-N-acetylneuraminate metabolic process [inference]

CMP-N-acetylneuraminate biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

phosphorus metabolic process [inference]

CMP-N-acetylneuraminate metabolic process [inference]

CMP-N-acetylneuraminate biosynthetic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

CMP-N-acetylneuraminate metabolic process [inference]

CMP-N-acetylneuraminate biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

cellular biosynthetic process [inference]

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

CMP-N-acetylneuraminate metabolic process [inference]

CMP-N-acetylneuraminate biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

CMP-N-acetylneuraminate metabolic process [inference]

CMP-N-acetylneuraminate biosynthetic process

protein metabolic process [inference]

protein modification process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

CMP-N-acetylneuraminate metabolic process [inference]

CMP-N-acetylneuraminate biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process

macromolecule modification [inference]

protein modification process

carbohydrate derivative metabolic process [inference]

amino sugar metabolic process [inference]

N-acetylneuraminate metabolic process

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

CMP-N-acetylneuraminate metabolic process [inference]

CMP-N-acetylneuraminate biosynthetic process

carbohydrate derivative biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

CMP-N-acetylneuraminate metabolic process [inference]

CMP-N-acetylneuraminate biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

organonitrogen compound metabolic process [inference]

N-acetylneuraminate metabolic process

protein metabolic process [inference]

protein modification process

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

CMP-N-acetylneuraminate metabolic process [inference]

CMP-N-acetylneuraminate biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

phosphorus metabolic process [inference]

CMP-N-acetylneuraminate metabolic process [inference]

CMP-N-acetylneuraminate biosynthetic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

CMP-N-acetylneuraminate metabolic process [inference]

CMP-N-acetylneuraminate biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

cellular biosynthetic process [inference]

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

CMP-N-acetylneuraminate metabolic process [inference]

CMP-N-acetylneuraminate biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

CMP-N-acetylneuraminate biosynthetic process

transmembrane transport [inference]

nucleotide-sugar transmembrane transport [inference]

pyrimidine nucleotide-sugar transmembrane transport [inference]

CMP-N-acetylneuraminate transmembrane transport

localization [inference]

establishment of localization [inference]

transport [inference]

transmembrane transport [inference]

nucleotide-sugar transmembrane transport [inference]

pyrimidine nucleotide-sugar transmembrane transport [inference]

CMP-N-acetylneuraminate transmembrane transport

organic substance transport [inference]

organic anion transport [inference]

CMP-N-acetylneuraminate transmembrane transport

nucleobase-containing compound transport [inference]

nucleotide-sugar transmembrane transport [inference]

pyrimidine nucleotide-sugar transmembrane transport [inference]

CMP-N-acetylneuraminate transmembrane transport

carbohydrate derivative transport [inference]

nucleotide-sugar transmembrane transport [inference]

pyrimidine nucleotide-sugar transmembrane transport [inference]

CMP-N-acetylneuraminate transmembrane transport

nitrogen compound transport [inference]

nucleobase-containing compound transport [inference]

nucleotide-sugar transmembrane transport [inference]

pyrimidine nucleotide-sugar transmembrane transport [inference]

CMP-N-acetylneuraminate transmembrane transport

Displaying **all 5** entries
GO Term	Evidence Code	PMID
Golgi membrane	TAS
Golgi membrane	IBA
Golgi apparatus	TAS	9644260
plasma membrane	TAS	9644260
membrane	ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying **all 5** entries
GO Term	Evidence Code	PMID
CMP-N-acetylneuraminate transmembrane transporter activity	ISS
CMP-N-acetylneuraminate transmembrane transporter activity	TAS
CMP-N-acetylneuraminate transmembrane transporter activity	IBA
protein binding	IPI	32296183
antiporter activity	ISS

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic anion transmembrane transporter activity [inference]

CMP-N-acetylneuraminate transmembrane transporter activity

nucleobase-containing compound transmembrane transporter activity [inference]

nucleotide-sugar transmembrane transporter activity [inference]

pyrimidine nucleotide-sugar transmembrane transporter activity [inference]

CMP-N-acetylneuraminate transmembrane transporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

antiporter activity

carbohydrate derivative transmembrane transporter activity [inference]

nucleotide-sugar transmembrane transporter activity [inference]

pyrimidine nucleotide-sugar transmembrane transporter activity [inference]

CMP-N-acetylneuraminate transmembrane transporter activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

GlycoGene Database (GGDB)

GGDB ID

gg178

Gene Symbol

SLC35A1

Orthologous Gene

Displaying **all 2** entries
Species	Protein	mRNA
Mus musculus	NP_036025	NM_011895
Rattus norvegicus	XP_232884	XM_232884

KEGG BRITE Database

Orthology

K15272

Name

solute carrier family 35 (UDP-sugar transporter), member A1/2/3

References

12759756

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0070258	congenital disorder of glycosylation type IIf	Glyco-Disease Genes Database Alliance of Genome Resources

The Human Phenotype Ontology

Displaying entries **1 - 10** of 35 in total

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HPO ID	HPO Term
HP:0000007	Autosomal recessive inheritance
HP:0000093	Proteinuria
HP:0000252	Microcephaly
HP:0000322	Short philtrum
HP:0000465	Webbed neck
HP:0000490	Deeply set eye
HP:0000601	Hypotelorism
HP:0000639	Nystagmus
HP:0001249	Intellectual disability
HP:0001250	Seizure