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alpha 1,4-galactosyltransferase (P1PK blood group)

Summary

Gene Symbol

A4GALT

Organism

Cercocebus atys (sooty mangabey)

External Links

NCBI Gene: 105598322
KEGG Gene ID: caty:105598322
PubChem: 105598322

Annotation

Keyword

Glycosyltransferase
Golgi apparatus
Lipid biosynthesis
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A2K5KWH5	Alpha-1,4-N-acetylglucosaminyltransferase Alpha-1,4-galactosyltransferase Globotriaosylceramide synthase UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
protein O-linked glycosylation	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

Displaying 1 entry
GO Term	Evidence Code	PMID
acetylglucosaminyltransferase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Cercopithecoidea

Group Name

lactosylceramide 4-alpha-galactosyltransferase

Functional Category

J: Translation, ribosomal structure and biogenesis
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 8** entries
Gene Ontology
galactosyltransferase activity
globoside biosynthetic process
glycosphingolipid biosynthetic process
hexosyltransferase activity
lactosylceramide 4-alpha-galactosyltransferase activity
lipid metabolic process
plasma membrane organization
toxic substance binding

Displaying **all 3** entries
InterPro
Alpha 1,4-glycosyltransferase domain
Glycosyltransferase, DXD sugar-binding motif
Nucleotide-diphospho-sugar transferases

KEGG BRITE Database

Orthology

K01988

Name

lactosylceramide 4-alpha-galactosyltransferase [EC:2.4.1.228]

References

10748143

Reactions

Displaying **all 3** entries
KEGG Reaction	Enzyme	Acceptor	Product
R11375	2.4.1.228	G58896AZ	G12460DL
R11376	2.4.1.228	G00061MO	G33020YH
R05960	2.4.1.228	G84224TW	G00059MO

Rhea

RHEA:11924

a β-D-Gal-(1→4)-β-D-Glc-(1↔1)-Cer(d18:1(4E)) + UDP-α-D-galactose

H⁺ + a globoside Gb3Cer (d18:1(4E)) + UDP

Enzyme

2.4.1.228

PMID

Ortholog

Displaying entries **11 - 20** of 64 in total

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Species	Gene ID	Orthologous MAtrix
Oryctolagus cuniculus	100347783	RABIT15044
Callithrix jacchus	100399091	CALJA20165
Ailuropoda melanoleuca	100473471	AILME05094
Sus scrofa	100524987	PIGXX24962
Meleagris gallopavo	100550373	MELGA00770
Anolis carolinensis	100558212	ANOCA07401
Loxodonta africana	100654825	LOXAF04423
Cavia porcellus	100721247	CAVPO13227
Cricetulus griseus	100770462	CRIGR17465
Sarcophilus harrisii	100925030	SARHA05010

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements