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solute carrier family 19 member 2

Summary

Gene Symbol

SLC19A2

Organism

Homo sapiens (human)

External Links

NCBI Gene

10560

PubChem

10560

Alliance of Genome Resources

HGNC:10938

Annotation

Keyword

Acetylation
Alternative splicing
Cell membrane
Deafness
Diabetes mellitus
Disease variant
Glycoprotein
Phosphoprotein
Reference proteome
Transmembrane helix
Transport

Proteins

Displaying **all 3** entries
UniProt	Protein Name
O60779	Solute carrier family 19 member 2 Thiamine carrier 1
A0A024R928
A0A024R8Y5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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2

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GO Term	Evidence Code	PMID
thiamine transport	IBA IDA IMP NAS	10391222 10542220 33008889 35512554 35724964
thiamine-containing compound metabolic process	TAS
pyridoxine transport	IDA	33008889 35512554
thiamine diphosphate biosynthetic process	IEA
folic acid transport	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organonitrogen compound metabolic process [inference]

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organonitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

heterocycle biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

aromatic compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

sulfur compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organic substance biosynthetic process [inference]

organophosphate biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organic cyclic compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organonitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

aromatic compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound metabolic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

sulfur compound metabolic process [inference]

thiamine-containing compound metabolic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

sulfur compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

organophosphate metabolic process [inference]

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

thiamine diphosphate biosynthetic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

heterocycle biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

aromatic compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

sulfur compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

small molecule metabolic process [inference]

vitamin metabolic process [inference]

water-soluble vitamin metabolic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound metabolic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organic substance metabolic process [inference]

organophosphate metabolic process [inference]

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organic cyclic compound metabolic process [inference]

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organic cyclic compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organonitrogen compound metabolic process [inference]

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organonitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organic substance biosynthetic process [inference]

organophosphate biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organic cyclic compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organonitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

aromatic compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound metabolic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

sulfur compound metabolic process [inference]

thiamine-containing compound metabolic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

sulfur compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

organophosphate metabolic process [inference]

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

thiamine diphosphate biosynthetic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

heterocycle biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

aromatic compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

sulfur compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

transmembrane transport

vitamin transmembrane transport [inference]

thiamine transmembrane transport

azole transmembrane transport [inference]

thiamine transmembrane transport

pyrimidine-containing compound transmembrane transport [inference]

thiamine transmembrane transport

reproductive process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

multicellular organismal reproductive process [inference]

gamete generation [inference]

male gamete generation [inference]

spermatogenesis

developmental process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

localization [inference]

establishment of localization [inference]

transport [inference]

vitamin transport [inference]

folic acid transport

thiamine transport

thiamine transmembrane transport

vitamin B6 transport [inference]

pyridoxine transport

vitamin transmembrane transport [inference]

thiamine transmembrane transport

transmembrane transport

vitamin transmembrane transport [inference]

thiamine transmembrane transport

azole transmembrane transport [inference]

thiamine transmembrane transport

pyrimidine-containing compound transmembrane transport [inference]

thiamine transmembrane transport

organic substance transport [inference]

organic cation transport [inference]

thiamine transport

thiamine transmembrane transport

organic anion transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

folic acid transport

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

folic acid transport

organic hydroxy compound transport [inference]

pyridoxine transport

vitamin B6 transport [inference]

pyridoxine transport

azole transmembrane transport [inference]

thiamine transmembrane transport

modified amino acid transport [inference]

folic acid transport

pyrimidine-containing compound transmembrane transport [inference]

thiamine transmembrane transport

nitrogen compound transport [inference]

thiamine transport

thiamine transmembrane transport

vitamin B6 transport [inference]

pyridoxine transport

amide transport [inference]

folic acid transport

azole transmembrane transport [inference]

thiamine transmembrane transport

modified amino acid transport [inference]

folic acid transport

pyrimidine-containing compound transmembrane transport [inference]

thiamine transmembrane transport

sulfur compound transport [inference]

thiamine transport

thiamine transmembrane transport

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane	NAS	10542220
plasma membrane	IBA IDA TAS	21836059

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	21836059
thiamine transmembrane transporter activity	IBA IDA ISS TAS	10542220 21836059
folic acid transmembrane transporter activity	NAS	10542220

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

folic acid transmembrane transporter activity

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

folic acid transmembrane transporter activity

organic cation transmembrane transporter activity [inference]

thiamine transmembrane transporter activity

amide transmembrane transporter activity [inference]

folic acid transmembrane transporter activity

modified amino acid transmembrane transporter activity [inference]

folic acid transmembrane transporter activity

vitamin transmembrane transporter activity [inference]

azole transmembrane transporter activity [inference]

thiamine transmembrane transporter activity

sulfur compound transmembrane transporter activity [inference]

thiamine transmembrane transporter activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

transporter

Functional Category

O: Posttranslational modification, protein turnover, chaperones
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
vitamin transmembrane transport
vitamin transport

Displaying **all 2** entries
InterPro
MFS transporter superfamily
Reduced folate carrier

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0090117	thiamine-responsive megaloblastic anemia syndrome	Alliance of Genome Resources
DOID:13382	megaloblastic anemia	Alliance of Genome Resources
DOID:784	chronic kidney disease	Alliance of Genome Resources
DOID:9351	diabetes mellitus	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 90 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	34679		FB:FBgn0032449
Drosophila melanogaster	41307		FB:FBgn0037845
Drosophila melanogaster	41308		FB:FBgn0037846
Mus musculus	116914		MGI:1928761	MOUSE29246
Caenorhabditis elegans	179544		WB:WBGene00007388
Rattus norvegicus	289175		RGD:1308611	RATNO07612
Xenopus laevis	431907		Xenbase:XB-GENE-953260
Pan troglodytes	469575	9598_0:0000ee		PANTR22972
Canis lupus familiaris	490353			CANLF17275
Bos taurus	532860			BOVIN08192

GlyTouCan

GlyComb

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UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements