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Guidelines

MIRAGE

podoplanin

Summary

Gene Symbol

PDPN

Organism

Homo sapiens (human)

External Links

NCBI Gene

10630

PubChem

10630

Alliance of Genome Resources

HGNC:29602

JoGo

PDPN

TogoVar

PDPN

Annotation

Keyword

3D-structure
Alternative splicing
Cell junction
Cell membrane
Cell projection
Cell shape
Cytoplasm
Developmental protein
Direct protein sequencing
Proteomics identification
Reference proteome
Sialic acid
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q86YL7	Aggrus Glycoprotein 36 PA2.26 antigen T1-alpha

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 27 in total

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GO Term	Evidence Code	PMID
lymphangiogenesis	ISS
water transport	ISS
amino acid transport	ISS
cell adhesion	IBA
signal transduction	IBA

GO Hierarchy

biological process

cellular process [inference]

cell activation [inference]

platelet activation

cell adhesion

signal transduction

intracellular signal transduction [inference]

small GTPase mediated signal transduction [inference]

Ras protein signal transduction [inference]

Rho protein signal transduction

actin filament-based process [inference]

actin filament-based movement [inference]

actin-mediated cell contraction

cellular developmental process [inference]

cell fate commitment [inference]

epithelial cell fate commitment [inference]

endothelial cell fate commitment [inference]

lymphatic endothelial cell fate commitment

cell motility [inference]

wound healing, spreading of cells

multicellular organismal process [inference]

cell activation [inference]

platelet activation

developmental process [inference]

anatomical structure morphogenesis [inference]

lymphangiogenesis

anatomical structure formation involved in morphogenesis [inference]

lymphangiogenesis

anatomical structure development [inference]

animal organ development [inference]

lung development

hematopoietic or lymphoid organ development [inference]

lymph node development

cellular developmental process [inference]

cell fate commitment [inference]

epithelial cell fate commitment [inference]

endothelial cell fate commitment [inference]

lymphatic endothelial cell fate commitment

localization [inference]

establishment of localization [inference]

transport [inference]

fluid transport [inference]

water transport

vitamin transport [inference]

folic acid transport

organic substance transport [inference]

water transport

organic anion transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

folic acid transport

amino acid transport

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

folic acid transport

amino acid transport

modified amino acid transport [inference]

folic acid transport

nitrogen compound transport [inference]

amino acid transport

amide transport [inference]

folic acid transport

modified amino acid transport [inference]

folic acid transport

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of biological process [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of homotypic cell-cell adhesion [inference]

positive regulation of platelet aggregation

positive regulation of cellular component organization [inference]

positive regulation of extracellular matrix organization [inference]

positive regulation of extracellular matrix disassembly

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition

positive regulation of multicellular organismal process [inference]

positive regulation of epithelial to mesenchymal transition

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of cell differentiation [inference]

regulation of epithelial to mesenchymal transition [inference]

positive regulation of epithelial to mesenchymal transition

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition

regulation of cellular process [inference]

signal transduction

intracellular signal transduction [inference]

small GTPase mediated signal transduction [inference]

Ras protein signal transduction [inference]

Rho protein signal transduction

regulation of cell adhesion [inference]

regulation of cell-substrate adhesion [inference]

regulation of substrate adhesion-dependent cell spreading

regulation of cell-cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of homotypic cell-cell adhesion [inference]

positive regulation of platelet aggregation

regulation of homotypic cell-cell adhesion [inference]

positive regulation of homotypic cell-cell adhesion [inference]

positive regulation of platelet aggregation

regulation of platelet aggregation [inference]

positive regulation of platelet aggregation

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of homotypic cell-cell adhesion [inference]

positive regulation of platelet aggregation

regulation of actin filament-based process [inference]

regulation of actin filament-based movement [inference]

regulation of myofibroblast contraction

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of cell differentiation [inference]

regulation of epithelial to mesenchymal transition [inference]

positive regulation of epithelial to mesenchymal transition

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of homotypic cell-cell adhesion [inference]

positive regulation of platelet aggregation

positive regulation of cellular component organization [inference]

positive regulation of extracellular matrix organization [inference]

positive regulation of extracellular matrix disassembly

positive regulation of cell motility [inference]

positive regulation of cell migration

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of cell activation [inference]

regulation of platelet activation [inference]

regulation of platelet aggregation [inference]

positive regulation of platelet aggregation

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

regulation of plasma membrane bounded cell projection organization [inference]

regulation of lamellipodium organization [inference]

regulation of lamellipodium morphogenesis

positive regulation of cellular component organization [inference]

positive regulation of extracellular matrix organization [inference]

positive regulation of extracellular matrix disassembly

regulation of extracellular matrix organization [inference]

regulation of extracellular matrix disassembly [inference]

positive regulation of extracellular matrix disassembly

positive regulation of extracellular matrix organization [inference]

positive regulation of extracellular matrix disassembly

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of platelet activation [inference]

regulation of platelet aggregation [inference]

positive regulation of platelet aggregation

positive regulation of multicellular organismal process [inference]

positive regulation of epithelial to mesenchymal transition

regulation of biological quality [inference]

regulation of cell shape

Displaying entries **1 - 5** of 25 in total

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GO Term	Evidence Code	PMID
ruffle	ISS
mitochondrion	IDA
cytosol	IDA	24275092
plasma membrane	ISS
plasma membrane	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

plasma membrane

plasma membrane region [inference]

cell projection membrane [inference]

membrane microdomain [inference]

membrane raft

anchoring junction

cell leading edge [inference]

leading edge of lamellipodium

leading edge membrane [inference]

cell projection

plasma membrane bounded cell projection [inference]

actin-based cell projection [inference]

filopodium

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular vesicle [inference]

cytoplasmic vesicle

tetraspanin-enriched microdomain

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GO Term	Evidence Code	PMID
signaling receptor binding	IDA	18215137
water transmembrane transporter activity	ISS
protein binding	IPI	17046996 17616532 18215137 18541721 19268462 20962267 25458834 32296183
folic acid transmembrane transporter activity	ISS
amino acid transmembrane transporter activity	ISS

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

inorganic molecular entity transmembrane transporter activity [inference]

water transmembrane transporter activity

water channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

water channel activity

amide transmembrane transporter activity [inference]

folic acid transmembrane transporter activity

modified amino acid transmembrane transporter activity [inference]

folic acid transmembrane transporter activity

vitamin transmembrane transporter activity [inference]

folic acid transmembrane transporter activity

salt transmembrane transporter activity [inference]

water transmembrane transporter activity

water channel activity

binding [inference]

protein binding

signaling receptor binding

cytokine binding [inference]

chemokine binding

protein-folding chaperone binding

Gene Ontology information from NCBI Gene and UniProt.

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026