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Standards Ontologies Notations
phospholipase C gamma 2

Summary
Gene Symbol
  • PLCG2
Organism
Apteryx mantelli (North Island brown kiwi)
NCBI Gene
106483269
KEGG Gene ID
aam:106483269
PubChem
106483269
Annotation
Keyword
  • Calcium
  • Hydrolase
  • Lipid degradation
  • Phosphoprotein
  • Reference proteome
  • Repeat
  • SH2 domain
  • SH3 domain
  • Transducer
Proteins
Displaying 1 entry
UniProt Protein Name
A0A8B7IG44
Annotation information from UniProt.
OrthoDB (Group)
Group level
Aves
Group Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
Functional Category
  • G: Carbohydrate transport and metabolism
  • M: Cell wall/membrane/envelope biogenesis
  • T: Signal transduction mechanisms
Displaying all 7 entries
Gene Ontology
hydrolase activity
lipid metabolic process
phosphatidylinositol phospholipase C activity
phosphatidylinositol-mediated signaling
phospholipid catabolic process
positive regulation of epithelial cell migration
release of sequestered calcium ion into cytosol
Displaying entries 1 - 10 of 17 in total
InterPro
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2, SH3 domain
C2 domain superfamily
C2 domain
EF-hand domain pair
PH-like domain superfamily
PLC-gamma, C-terminal SH2 domain
PLC-gamma, N-terminal SH2 domain
PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma
Phosphatidylinositol-specific phospholipase C, X domain
KEGG BRITE Database
Orthology
K05859
Name
phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
References
Rhea

RHEA:33179

H2O + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate)
H+ + a 1,2-diacyl-sn-glycerol + 1D-myo-inositol 1,4,5-trisphosphate
Enzyme
PMID
Ortholog
Displaying entries 1 - 10 of 74 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
415805 9031_0:00283d
100219388 59729_0:00241c
100549684 9103_0:002840
101799246 8839_0:002690
101811465 59894_0:0022cb
101869948 13146_0:003c8e
101914329 8954_0:00332a
102039725 48883_0:002d12
102058636 345164_0:00321d
102064935 44394_0:001cda
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024