GlyCosmos Portal

GlyTouCan

Glycan Structure Repository

GlyComb

Glycoconjugate Repository

GlycoPOST

Glycomics MS raw data Repository

UniCarb-DR

Glycomics MS Repository for glycan annotations from GlycoWorkbench

LM-GlycoRepo

Repository for lectin-assisted multimodality data

All Resources

Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms

Other Information

Release Statistics Download

Tools

Glycan Converters

LM-GlycomeAtlas

Search Tools

Cross Search Glycan Search Publication Search Programmatic Access

farnesyl-diphosphate farnesyltransferase 1

Summary

Gene Symbol

FDFT1

Organism

Thamnophis sirtalis

External Links

NCBI Gene: 106546572
KEGG Gene ID: tsr:106546572
PubChem: 106546572

Annotation

Keyword

Multifunctional enzyme
Reference proteome
Transferase

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A6I9Y4J1
A0A6I9Y9M7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cholesterol biosynthetic process	IEA	30032202
farnesyl diphosphate metabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

farnesyl diphosphate metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

farnesyl diphosphate metabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

farnesyl diphosphate metabolic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

farnesyl diphosphate metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

farnesyl diphosphate metabolic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

farnesyl diphosphate metabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

secondary alcohol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

farnesyl diphosphate metabolic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

farnesyl diphosphate metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

farnesyl diphosphate metabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

secondary alcohol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

farnesyl diphosphate metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

farnesyl diphosphate metabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

farnesyl diphosphate metabolic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

farnesyl diphosphate metabolic process

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
squalene synthase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring alkyl or aryl (other than methyl) groups [inference]

prenyltransferase activity [inference]

farnesyltranstransferase activity [inference]

squalene synthase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Squalene synthase

Functional Category

H: Coenzyme transport and metabolism
I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 8** entries
Gene Ontology
cholesterol biosynthetic process
ergosterol biosynthetic process
farnesyl diphosphate metabolic process
farnesyl-diphosphate farnesyltransferase activity
farnesyltranstransferase activity
lipid biosynthetic process
squalene synthase activity
transferase activity

Displaying **all 6** entries
InterPro
Isoprenoid synthase domain superfamily
Squalene synthase-like
Squalene/phytoene synthase, conserved site
Squalene/phytoene synthase
Trans-isoprenyl diphosphate synthases, eukaryotic-type
Trans-isoprenyl diphosphate synthases, head-to-head

KEGG BRITE Database

Orthology

K00801

Name

farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21]

References

Rhea

H⁺ + (2E,6E)-farnesyl diphosphate + NADH

squalene + diphosphate + NAD⁺

Enzyme

2.5.1.21

PMID

H⁺ + (2E,6E)-farnesyl diphosphate + NADPH

squalene + diphosphate + NADP⁺

Enzyme

2.5.1.21

PMID

Ortholog

Displaying entries **21 - 30** of 30 in total

« First

‹ Prev

1

2

3
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Sphaerodactylus townsendi	125444834	933632_0:000314
Sphaerodactylus townsendi	125444876	933632_0:0001d5
Hemicordylus capensis	128324183	884348_0:0005c4
Podarcis raffonei	128411411	65483_0:001394
Eublepharis macularius	129329622	481883_0:00069d
Eublepharis macularius	129329927	481883_0:00001d
Eublepharis macularius	129330729	481883_0:00051e
Eublepharis macularius	129335438	481883_0:0000b8
Euleptes europaea	130481161	460621_0:002361
Ahaetulla prasina	131189043	499056_0:000978

About Release Notes Help Feedback

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: support@glycosmos.org

GlyCosmos Portal v4.1.0

Last updated: December 9, 2024