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carboxylesterase 1
Summary
- Gene Symbol
-
- CES1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cytoplasm
- Direct protein sequencing
- Disulfide bond
- Endoplasmic reticulum
- Glycoprotein
- Lipid droplet
- Lipid metabolism
- Phosphoprotein
- Reference proteome
- Serine esterase
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| P23141 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cholesterol biosynthetic process | ||
| cholesterol metabolic process | ||
| response to toxic substance | ||
| positive regulation of cholesterol efflux | ||
| negative regulation of cholesterol storage |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytoplasm | ||
| endoplasmic reticulum | ||
| endoplasmic reticulum | ||
| endoplasmic reticulum lumen | ||
| lipid droplet |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| sterol esterase activity | ||
| protein binding | ||
| methylumbelliferyl-acetate deacetylase activity | ||
| carboxylic ester hydrolase activity | ||
| carboxylesterase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- carboxylesterase
- Functional Category
-
- E: Amino acid transport and metabolism
- I: Lipid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| hydrolase activity |
| InterPro |
|---|
| Alpha/Beta hydrolase fold |
| Carboxylesterase, type B |
Disease
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 1066 | ZFIN:ZDB-GENE-030131-9563 | ||
| 8824 | ZFIN:ZDB-GENE-030131-9563 | ||
| 12623 | ZFIN:ZDB-GENE-030131-9563 | ||
| 13884 | ZFIN:ZDB-GENE-030131-9563 | ||
| 13897 | ZFIN:ZDB-GENE-030131-9563 | ||
| 13909 | ZFIN:ZDB-GENE-030131-9563 | ||
| 23491 | ZFIN:ZDB-GENE-030131-9563 | ||
| 24346 | ZFIN:ZDB-GENE-030131-9563 | ||
| 39392 | ZFIN:ZDB-GENE-030131-9563 | ||
| 39393 | ZFIN:ZDB-GENE-030131-9563 |
